Ligand ID: IU5

Drugbank ID:
Ursodeoxycholic acid
(DB01586)

Indication:
Ursodeoxycholic acid is a bile acid used for the treatment of primary biliary cirrhosis (PBC), dissolution of radiolucent gallstones in patients with a functioning gallbladder, and treatment of hepatobiliary disorders associated with cystic fibrosis in pediatric patients.


LIST OF BINDING INTERFACES for query 'DB01586'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)
DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details
1IHI_A_IU5A3261ihi IU5Ursodeoxycholic acid
(DB01586) 		Homo sapiens 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE Aldo_ket_red 10TYR A  24
VAL A  54
TYR A  55
TRP A  86
HIS A 117
VAL A 128
ILE A 129
GLU A 224
TRP A 227
LEU A 308
IU5 A 326
1OT7_B_IU5B10021ot7 IU5Ursodeoxycholic acid
(DB01586) 		Rattus norvegicus;
synthetic construct 		BILE ACID RECEPTOR Hormone_recep 18MET B 262
LEU B 284
MET B 287
ALA B 288
HIS B 291
MET B 325
PHE B 326
ARG B 328
SER B 329
ILE B 332
PHE B 333
LEU B 345
ILE B 349
TYR B 358
TYR B 366
HIS B 444
TRP B 451
TRP B 466
IU5 B1002
DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details