
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
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PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
---|---|---|---|---|---|---|---|
1s2c | FLF | Flufenamic acid (DB02266) | Flufenamic acid is an analgesic drug used to relieve pain associated with rheumatoid diseases. | ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3 (Homo sapiens) | Aldo_ket_red | ||
2f38 | 15M | Bimatoprost (DB00905) | Bimatoprost is a prostaglandin analog used to treat hypotrichosis of the eyelashes and intraocular pressure in open angle glaucoma or ocular hypertension. | ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3 (Homo sapiens) | Aldo_ket_red | ||
3r43 | ID8 | Mefenamic acid (DB00784) | Mefenamic acid is an NSAID used to treat mild to moderate pain for no more than a week, and primary dysmenorrhea. | ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3 (Homo sapiens) | Aldo_ket_red | ||
3r58 | NPS | Naproxen (DB00788) | Naproxen is an NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain. | ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3 (Homo sapiens) | Aldo_ket_red | ||
3r6i | JMS | Meclofenamic acid (DB00939) | Meclofenamic acid is an NSAID used to treat mild to moderate pain, primary dysmenorrhea, heavy menstrual blood loss, rheumatoid arthritis, and osteoarthritis. | ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3 (Homo sapiens) | Aldo_ket_red | ||
3r7m | SUZ | Sulindac (DB00605) | Sulindac is an NSAID used to treat osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute subacromial bursitis or supraspinatus tendinitis, and acute gouty arthritis. | ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3 (Homo sapiens) | Aldo_ket_red | ||
3r8g | IZP | Ibuprofen (DB01050) | Ibuprofen is an NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation. | ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3 (Homo sapiens) | Aldo_ket_red | ||
3ugr | IMN | Indomethacin (DB00328) | Indomethacin is a nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants. | ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3 (Homo sapiens) | Aldo_ket_red | ||
4yvv | GBM | Glyburide (DB01016) | Glyburide is a sulfonylurea used in the treatment of non insulin dependent diabetes mellitus. | ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3 (Homo sapiens) | Aldo_ket_red | ||
4yvx | GMR | Glimepiride (DB00222) | Glimepiride is a sulfonylurea drug used to treat type 2 diabetes mellitus. | ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3 (Homo sapiens) | Aldo_ket_red | ||
4zfc | GCZ | Gliclazide (DB01120) | Gliclazide is a sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus. | ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3 (Homo sapiens) | Aldo_ket_red | ||
PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |