Results: Ligand

Ligand ID: NPS

Drugbank ID:
Naproxen
(DB00788)

Indication:
Naproxen is an NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain.

LIST OF BINDING INTERFACES for query 'NPS'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
2VDB_A_NPSA1591	2vdb	NPS	Naproxen (DB00788)	Peptostreptococcus magnus; homo sapiens	SERUM ALBUMIN	Serum_albumin	11	ILE A 142 ARG A 145 HIS A 146 PHE A 149 LEU A 154 PHE A 157 TYR A 161 LEU A 185 ARG A 186 GLY A 189 LYS A 190	NPS A1591
3NT1_A_NPSA5	3nt1	NPS	Naproxen (DB00788)	Mus musculus	PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE 2	An_peroxidase EGF	18	VAL A 116 ARG A 120 VAL A 349 LEU A 352 SER A 353 TYR A 355 LEU A 359 PHE A 381 LEU A 384 TYR A 385 TRP A 387 PHE A 518 MET A 522 VAL A 523 GLY A 526 ALA A 527 SER A 530 LEU A 531	NPS A 5
3R58_A_NPSA332	3r58	NPS	Naproxen (DB00788)	Homo sapiens	ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3	Aldo_ket_red	14	TYR A 24 LEU A 54 TYR A 55 TRP A 86 HIS A 117 SER A 118 MET A 120 ASN A 167 TYR A 216 TRP A 227 PHE A 306 PHE A 311 PRO A 318 TYR A 319	NPS A 332
4FJP_A_NPSA711	4fjp	NPS	Naproxen (DB00788)	Bos taurus	LACTOTRANSFERRIN	Transferrin	9	THR A 430 GLU A 431 GLY A 432 ALA A 592 PRO A 593 ASN A 594 GLU A 659 TYR A 660 GLY A 662	NPS A 711
4JQ1_A_NPSA401	4jq1	NPS	Naproxen (DB00788)	Homo sapiens	ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2	Aldo_ket_red	11	TYR A 24 VAL A 54 TYR A 55 TRP A 86 HIS A 117 VAL A 128 ILE A 129 HIS A 222 TRP A 227 LEU A 306 LEU A 308	NPS A 401
4OR0_A_NPSA601	4or0	NPS	Naproxen (DB00788)	Bos taurus	SERUM ALBUMIN	Serum_albumin	18	LEU A 386 ASN A 390 CYS A 391 PHE A 402 LEU A 406 ARG A 409 TYR A 410 LYS A 413 LEU A 429 VAL A 432 GLY A 433 CYS A 437 THR A 448 LEU A 452 LEU A 456 ARG A 484 PHE A 487 SER A 488	NPS A 601
4OR0_A_NPSA602	4or0	NPS	Naproxen (DB00788)	Bos taurus	SERUM ALBUMIN	Serum_albumin	14	PHE A 205 ARG A 208 ALA A 209 ALA A 212 ASP A 323 LEU A 326 GLY A 327 LEU A 330 LEU A 346 ALA A 349 LYS A 350 SER A 479 LEU A 480 VAL A 481	NPS A 602
4OR0_A_NPSA603	4or0	NPS	Naproxen (DB00788)	Bos taurus	SERUM ALBUMIN	Serum_albumin	14	ARG A 194 LEU A 197 ARG A 198 SER A 201 ALA A 209 TRP A 213 ARG A 217 VAL A 342 SER A 343 LEU A 346 ASP A 450 LEU A 454 LEU A 480 VAL A 481	NPS A 603
4PO0_A_NPSA601	4po0	NPS	Naproxen (DB00788)	Oryctolagus cuniculus	SERUM ALBUMIN	Serum_albumin	17	LEU A 387 VAL A 388 ASN A 391 CYS A 392 PHE A 403 LEU A 407 ARG A 410 TYR A 411 LYS A 414 LEU A 430 VAL A 433 CYS A 438 VAL A 449 LEU A 453 ARG A 485 PHE A 488 SER A 489	NPS A 601
4PO0_A_NPSA602	4po0	NPS	Naproxen (DB00788)	Oryctolagus cuniculus	SERUM ALBUMIN	Serum_albumin	12	ARG A 209 LYS A 212 ALA A 213 LEU A 216 ASP A 324 LEU A 327 GLY A 328 LEU A 331 LEU A 347 GLY A 350 LYS A 351 GLU A 354	NPS A 602
4PO0_A_NPSA603	4po0	NPS	Naproxen (DB00788)	Oryctolagus cuniculus	SERUM ALBUMIN	Serum_albumin	11	LEU A 394 LEU A 398 ASN A 402 ASN A 405 ALA A 406 VAL A 409 LEU A 529 ASN A 541 LEU A 544 LYS A 545 VAL A 548	NPS A 603
4ZBR_A_NPSA602	4zbr	NPS	Naproxen (DB00788)	Equus caballus	SERUM ALBUMIN	Serum_albumin	18	LEU A 386 VAL A 387 ASN A 390 CYS A 391 PHE A 402 LEU A 406 ARG A 409 TYR A 410 LYS A 413 LEU A 429 VAL A 432 GLY A 433 CYS A 437 SER A 448 LEU A 452 ARG A 484 PHE A 487 SER A 488	NPS A 602
4ZBR_A_NPSA603	4zbr	NPS	Naproxen (DB00788)	Equus caballus	SERUM ALBUMIN	Serum_albumin	13	ARG A 208 ALA A 209 ALA A 212 ASP A 323 LEU A 326 GLY A 327 LEU A 330 LEU A 346 ALA A 349 LYS A 350 SER A 479 LEU A 480 ALA A 481	NPS A 603
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["2VDB_A_NPSA1591","2vdb","NPS","Naproxen (DB00788)","Peptostreptococcus magnus;homo sapiens","SERUM ALBUMIN","Serum_albumin",11,"ILE A 142;ARG A 145;HIS A 146;PHE A 149;LEU A 154;PHE A 157;TYR A 161;LEU A 185;ARG A 186;GLY A 189;LYS A 190","NPS A1591\r"],["3NT1_A_NPSA5","3nt1","NPS","Naproxen (DB00788)","Mus musculus","PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE 2","An_peroxidase;EGF",18,"VAL A 116;ARG A 120;VAL A 349;LEU A 352;SER A 353;TYR A 355;LEU A 359;PHE A 381;LEU A 384;TYR A 385;TRP A 387;PHE A 518;MET A 522;VAL A 523;GLY A 526;ALA A 527;SER A 530;LEU A 531","NPS A   5\r"],["3R58_A_NPSA332","3r58","NPS","Naproxen (DB00788)","Homo sapiens","ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3","Aldo_ket_red",14,"TYR A  24;LEU A  54;TYR A  55;TRP A  86;HIS A 117;SER A 118;MET A 120;ASN A 167;TYR A 216;TRP A 227;PHE A 306;PHE A 311;PRO A 318;TYR A 319","NPS A 332\r"],["4FJP_A_NPSA711","4fjp","NPS","Naproxen (DB00788)","Bos taurus","LACTOTRANSFERRIN","Transferrin",9,"THR A 430;GLU A 431;GLY A 432;ALA A 592;PRO A 593;ASN A 594;GLU A 659;TYR A 660;GLY A 662","NPS A 711\r"],["4JQ1_A_NPSA401","4jq1","NPS","Naproxen (DB00788)","Homo sapiens","ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2","Aldo_ket_red",11,"TYR A  24;VAL A  54;TYR A  55;TRP A  86;HIS A 117;VAL A 128;ILE A 129;HIS A 222;TRP A 227;LEU A 306;LEU A 308","NPS A 401\r"],["4OR0_A_NPSA601","4or0","NPS","Naproxen (DB00788)","Bos taurus","SERUM ALBUMIN","Serum_albumin",18,"LEU A 386;ASN A 390;CYS A 391;PHE A 402;LEU A 406;ARG A 409;TYR A 410;LYS A 413;LEU A 429;VAL A 432;GLY A 433;CYS A 437;THR A 448;LEU A 452;LEU A 456;ARG A 484;PHE A 487;SER A 488","NPS A 601\r"],["4OR0_A_NPSA602","4or0","NPS","Naproxen (DB00788)","Bos taurus","SERUM ALBUMIN","Serum_albumin",14,"PHE A 205;ARG A 208;ALA A 209;ALA A 212;ASP A 323;LEU A 326;GLY A 327;LEU A 330;LEU A 346;ALA A 349;LYS A 350;SER A 479;LEU A 480;VAL A 481","NPS A 602\r"],["4OR0_A_NPSA603","4or0","NPS","Naproxen (DB00788)","Bos taurus","SERUM ALBUMIN","Serum_albumin",14,"ARG A 194;LEU A 197;ARG A 198;SER A 201;ALA A 209;TRP A 213;ARG A 217;VAL A 342;SER A 343;LEU A 346;ASP A 450;LEU A 454;LEU A 480;VAL A 481","NPS A 603\r"],["4PO0_A_NPSA601","4po0","NPS","Naproxen (DB00788)","Oryctolagus cuniculus","SERUM ALBUMIN","Serum_albumin",17,"LEU A 387;VAL A 388;ASN A 391;CYS A 392;PHE A 403;LEU A 407;ARG A 410;TYR A 411;LYS A 414;LEU A 430;VAL A 433;CYS A 438;VAL A 449;LEU A 453;ARG A 485;PHE A 488;SER A 489","NPS A 601\r"],["4PO0_A_NPSA602","4po0","NPS","Naproxen (DB00788)","Oryctolagus cuniculus","SERUM ALBUMIN","Serum_albumin",12,"ARG A 209;LYS A 212;ALA A 213;LEU A 216;ASP A 324;LEU A 327;GLY A 328;LEU A 331;LEU A 347;GLY A 350;LYS A 351;GLU A 354","NPS A 602\r"],["4PO0_A_NPSA603","4po0","NPS","Naproxen (DB00788)","Oryctolagus cuniculus","SERUM ALBUMIN","Serum_albumin",11,"LEU A 394;LEU A 398;ASN A 402;ASN A 405;ALA A 406;VAL A 409;LEU A 529;ASN A 541;LEU A 544;LYS A 545;VAL A 548","NPS A 603\r"],["4ZBR_A_NPSA602","4zbr","NPS","Naproxen (DB00788)","Equus caballus","SERUM ALBUMIN","Serum_albumin",18,"LEU A 386;VAL A 387;ASN A 390;CYS A 391;PHE A 402;LEU A 406;ARG A 409;TYR A 410;LYS A 413;LEU A 429;VAL A 432;GLY A 433;CYS A 437;SER A 448;LEU A 452;ARG A 484;PHE A 487;SER A 488","NPS A 602\r"],["4ZBR_A_NPSA603","4zbr","NPS","Naproxen (DB00788)","Equus caballus","SERUM ALBUMIN","Serum_albumin",13,"ARG A 208;ALA A 209;ALA A 212;ASP A 323;LEU A 326;GLY A 327;LEU A 330;LEU A 346;ALA A 349;LYS A 350;SER A 479;LEU A 480;ALA A 481","NPS A 603\r"]]