Results: Ligand

Ligand ID: GBM

Drugbank ID:
Glyburide
(DB01016)

Indication:
Glyburide is a sulfonylurea used in the treatment of non insulin dependent diabetes mellitus.

LIST OF BINDING INTERFACES for query 'DB01016'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
4YVP_A_GBMA402	4yvp	GBM	Glyburide (DB01016)	Homo sapiens	ALDO-KETO REDUCTASE FAMILY 1 MEMBER C1	Aldo_ket_red	16	TYR A 24 LEU A 54 TYR A 55 ASN A 56 TRP A 86 HIS A 117 PHE A 118 VAL A 128 ILE A 129 ASN A 167 HIS A 222 GLU A 224 TRP A 227 LEU A 306 LEU A 308 PHE A 311	GBM A 402
4YVV_A_GBMA402	4yvv	GBM	Glyburide (DB01016)	Homo sapiens	ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3	Aldo_ket_red	9	TYR A 24 LEU A 54 TYR A 55 TRP A 86 HIS A 117 ASN A 167 TYR A 216 TRP A 227 PHE A 306	GBM A 402
5IFU_A_GBMA801	5ifu	GBM	Glyburide (DB01016)	Plasmodium falciparum (isolate 3d7)	PROLINE--TRNA LIGASE	HGTP_anticodon ProRS-C_1 tRNA-synt_2b	19	PHE A 262 SER A 263 TYR A 266 ILE A 270 ILE A 276 TYR A 285 LEU A 287 ALA A 291 THR A 402 GLU A 404 ASN A 470 ILE A 474 THR A 513 ARG A 514 ILE A 516 GLY A 517 ILE A 520 MET A 521 TYR A 746	GBM A 801
6BAA_E_GBME2001	6baa	GBM	Glyburide (DB01016)	Rattus norvegicus; cricetus cricetus	ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8	ABC_membrane ABC_tran	17	ARG E 306 TYR E 377 ILE E 381 MET E 429 TRP E 430 PHE E 433 LEU E 434 ASN E 437 MET E 441 THR E 588 LEU E 592 SER E1238 LEU E1241 THR E1242 ASN E1245 ARG E1246 ARG E1300	GBM E2001
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["4YVP_A_GBMA402","4yvp","GBM","Glyburide (DB01016)","Homo sapiens","ALDO-KETO REDUCTASE FAMILY 1 MEMBER C1","Aldo_ket_red",16,"TYR A  24;LEU A  54;TYR A  55;ASN A  56;TRP A  86;HIS A 117;PHE A 118;VAL A 128;ILE A 129;ASN A 167;HIS A 222;GLU A 224;TRP A 227;LEU A 306;LEU A 308;PHE A 311","GBM A 402\r"],["4YVV_A_GBMA402","4yvv","GBM","Glyburide (DB01016)","Homo sapiens","ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3","Aldo_ket_red",9,"TYR A  24;LEU A  54;TYR A  55;TRP A  86;HIS A 117;ASN A 167;TYR A 216;TRP A 227;PHE A 306","GBM A 402\r"],["5IFU_A_GBMA801","5ifu","GBM","Glyburide (DB01016)","Plasmodium falciparum (isolate 3d7)","PROLINE--TRNA LIGASE","HGTP_anticodon;ProRS-C_1;tRNA-synt_2b",19,"PHE A 262;SER A 263;TYR A 266;ILE A 270;ILE A 276;TYR A 285;LEU A 287;ALA A 291;THR A 402;GLU A 404;ASN A 470;ILE A 474;THR A 513;ARG A 514;ILE A 516;GLY A 517;ILE A 520;MET A 521;TYR A 746","GBM A 801\r"],["6BAA_E_GBME2001","6baa","GBM","Glyburide (DB01016)","Rattus norvegicus;cricetus cricetus","ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8","ABC_membrane;ABC_tran",17,"ARG E 306;TYR E 377;ILE E 381;MET E 429;TRP E 430;PHE E 433;LEU E 434;ASN E 437;MET E 441;THR E 588;LEU E 592;SER E1238;LEU E1241;THR E1242;ASN E1245;ARG E1246;ARG E1300","GBM E2001\r"]]