Results: Ligand

Ligand ID: IZP

Drugbank ID:
Ibuprofen
(DB01050)

Indication:
Ibuprofen is an NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation.

LIST OF BINDING INTERFACES for query 'DB01050'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
3P6G_A_IZPA133	3p6g	IZP	Ibuprofen (DB01050)	Homo sapiens	FATTY ACID-BINDING PROTEIN, ADIPOCYTE	Lipocalin	14	PHE A 16 TYR A 19 MET A 20 VAL A 23 VAL A 25 PRO A 38 ASP A 76 ARG A 78 ILE A 104 ARG A 106 VAL A 115 CYS A 117 ARG A 126 TYR A 128	IZP A 133
3R8G_A_IZPA409	3r8g	IZP	Ibuprofen (DB01050)	Homo sapiens	ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3	Aldo_ket_red	14	LEU A 54 TYR A 55 TRP A 86 HIS A 117 SER A 118 MET A 120 ASN A 167 TYR A 216 TRP A 227 PHE A 306 PHE A 311 TYR A 317 PRO A 318 TYR A 319	IZP A 409
3VM4_A_IZPA1	3vm4	IZP	Ibuprofen (DB01050)	Sphingomonas paucimobilis	FATTY ACID ALPHA-HYDROXYLASE	p450	11	LEU A 77 PHE A 169 ALA A 172 GLY A 173 ARG A 241 PRO A 242 ALA A 245 PHE A 287 PHE A 288 PRO A 289 PRO A 399	IZP A 1
4JTR_B_IZPB401	4jtr	IZP	Ibuprofen (DB01050)	Homo sapiens	ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2	Aldo_ket_red	9	TYR B 24 VAL B 54 TYR B 55 TRP B 86 HIS B 117 VAL B 128 ILE B 129 TRP B 227 LEU B 308	IZP B 401
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["3P6G_A_IZPA133","3p6g","IZP","Ibuprofen (DB01050)","Homo sapiens","FATTY ACID-BINDING PROTEIN, ADIPOCYTE","Lipocalin",14,"PHE A  16;TYR A  19;MET A  20;VAL A  23;VAL A  25;PRO A  38;ASP A  76;ARG A  78;ILE A 104;ARG A 106;VAL A 115;CYS A 117;ARG A 126;TYR A 128","IZP A 133\r"],["3R8G_A_IZPA409","3r8g","IZP","Ibuprofen (DB01050)","Homo sapiens","ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3","Aldo_ket_red",14,"LEU A  54;TYR A  55;TRP A  86;HIS A 117;SER A 118;MET A 120;ASN A 167;TYR A 216;TRP A 227;PHE A 306;PHE A 311;TYR A 317;PRO A 318;TYR A 319","IZP A 409\r"],["3VM4_A_IZPA1","3vm4","IZP","Ibuprofen (DB01050)","Sphingomonas paucimobilis","FATTY ACID ALPHA-HYDROXYLASE","p450",11,"LEU A  77;PHE A 169;ALA A 172;GLY A 173;ARG A 241;PRO A 242;ALA A 245;PHE A 287;PHE A 288;PRO A 289;PRO A 399","IZP A   1\r"],["4JTR_B_IZPB401","4jtr","IZP","Ibuprofen (DB01050)","Homo sapiens","ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2","Aldo_ket_red",9,"TYR B  24;VAL B  54;TYR B  55;TRP B  86;HIS B 117;VAL B 128;ILE B 129;TRP B 227;LEU B 308","IZP B 401\r"]]