Ligand ID: SUZ

Drugbank ID:
Sulindac
(DB00605)

Indication:
Sulindac is an NSAID used to treat osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute subacromial bursitis or supraspinatus tendinitis, and acute gouty arthritis.

LIST OF BINDING INTERFACES for query 'DB00605'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
2KAW_A_SUZA91	2kaw	SUZ	Sulindac (DB00605)	Mus musculus	SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-1	PDZ	15	PHE A  14 LEU A  15 GLY A  16 ILE A  17 SER A  18 ILE A  19 VAL A  20 GLY A  21 SER A  35 MET A  37 ASP A  68 VAL A  71 LEU A  74 ARG A  75 VAL A  78	SUZ A  91		Details
3R7M_A_SUZA332	3r7m	SUZ	Sulindac (DB00605)	Homo sapiens	ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3	Aldo_ket_red	12	TYR A  24 LEU A  54 TYR A  55 TRP A  86 HIS A 117 SER A 118 LEU A 122 ASN A 167 TRP A 227 PHE A 306 SER A 310 PHE A 311	SUZ A 332		Details
3U2C_A_SUZA2001	3u2c	SUZ	Sulindac (DB00605)	Homo sapiens	ALDOSE REDUCTASE	Aldo_ket_red	11	TRP A  20 VAL A  47 TYR A  48 HIS A 110 TRP A 111 PHE A 122 LEU A 124 TRP A 219 CYS A 298 LEU A 300 SER A 302	SUZ A2001		Details
4IKK_A_SUZA201	4ikk	SUZ	Sulindac (DB00605)	Homo sapiens	TRANSTHYRETIN	Transthyretin	11	LYS A  15 VAL A  16 LEU A  17 ALA A 108 ALA A 109 LEU A 110 SER B 115 SER A 117 SER B 117 THR A 118 THR A 119	SUZ A 201		Details
4JQ2_A_SUZA401	4jq2	SUZ	Sulindac (DB00605)	Homo sapiens	ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2	Aldo_ket_red	12	TYR A  24 VAL A  54 TYR A  55 TRP A  86 HIS A 117 VAL A 128 ILE A 129 HIS A 222 GLU A 224 TRP A 227 LEU A 306 LEU A 308	SUZ A 401		Details
4WEV_X_SUZX402	4wev	SUZ	Sulindac (DB00605)	Homo sapiens	ALDO-KETO REDUCTASE FAMILY 1 MEMBER B10	Aldo_ket_red	12	TRP X  21 VAL X  48 TYR X  49 HIS X 111 TRP X 112 PHE X 123 ARG X 125 GLY X 129 TRP X 220 CYS X 299 LEU X 301 GLN X 303	SUZ X 402		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["2KAW_A_SUZA91","2kaw","SUZ","Sulindac (DB00605)","Mus musculus","SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-1","PDZ",15,"PHE A 14;LEU A 15;GLY A 16;ILE A 17;SER A 18;ILE A 19;VAL A 20;GLY A 21;SER A 35;MET A 37;ASP A 68;VAL A 71;LEU A 74;ARG A 75;VAL A 78","SUZ A 91\r"],["3R7M_A_SUZA332","3r7m","SUZ","Sulindac (DB00605)","Homo sapiens","ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3","Aldo_ket_red",12,"TYR A 24;LEU A 54;TYR A 55;TRP A 86;HIS A 117;SER A 118;LEU A 122;ASN A 167;TRP A 227;PHE A 306;SER A 310;PHE A 311","SUZ A 332\r"],["3U2C_A_SUZA2001","3u2c","SUZ","Sulindac (DB00605)","Homo sapiens","ALDOSE REDUCTASE","Aldo_ket_red",11,"TRP A 20;VAL A 47;TYR A 48;HIS A 110;TRP A 111;PHE A 122;LEU A 124;TRP A 219;CYS A 298;LEU A 300;SER A 302","SUZ A2001\r"],["4IKK_A_SUZA201","4ikk","SUZ","Sulindac (DB00605)","Homo sapiens","TRANSTHYRETIN","Transthyretin",11,"LYS A 15;VAL A 16;LEU A 17;ALA A 108;ALA A 109;LEU A 110;SER B 115;SER A 117;SER B 117;THR A 118;THR A 119","SUZ A 201\r"],["4JQ2_A_SUZA401","4jq2","SUZ","Sulindac (DB00605)","Homo sapiens","ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2","Aldo_ket_red",12,"TYR A 24;VAL A 54;TYR A 55;TRP A 86;HIS A 117;VAL A 128;ILE A 129;HIS A 222;GLU A 224;TRP A 227;LEU A 306;LEU A 308","SUZ A 401\r"],["4WEV_X_SUZX402","4wev","SUZ","Sulindac (DB00605)","Homo sapiens","ALDO-KETO REDUCTASE FAMILY 1 MEMBER B10","Aldo_ket_red",12,"TRP X 21;VAL X 48;TYR X 49;HIS X 111;TRP X 112;PHE X 123;ARG X 125;GLY X 129;TRP X 220;CYS X 299;LEU X 301;GLN X 303","SUZ X 402\r"]]