LIST OF BINDING INTERFACES for query 'Toxoplasma gondii' in category 'SOURCE ORGANISM'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

PDB	Ligand	Drug	Indication	Macromolecule/ Organism	Pfam	Binding_Interfaces (View)	Details
1upf	URF	Fluorouracil (DB00544)	Fluorouracil is a pyrimidine analog used to treat basal cell carcinomas, and as an injection in palliative cancer treatment.	URACIL PHOSPHORIBOSYLTRANSFERASE (Toxoplasma gondii)	UPRTase	1UPF_D_URFD999	Details
2o2s	TCL	Triclosan (DB08604)	Triclosan is an antimicrobial agent in clinical setting for disinfection, and prevention of spread and growth of bacteria, fungus, and mildew.	ENOYL-ACYL CARRIER REDUCTASE (Toxoplasma gondii)	adh_short_C2	2O2S_A_TCLA705	Details
4ifg	1E8	Ibrutinib (DB09053)	Ibrutinib is an antineoplastic agent used to treat chronic lymphocytic leukemia, mantle cell lymphoma, and Waldenstrom's Macroglobulinemia.	CALMODULIN-DOMAIN PROTEIN KINASE 1 (Toxoplasma gondii)	EF-hand_7 Pkinase	4IFG_A_1E8A601	Details
5xiq	HFG	Halofuginone (DB04866)	Halofuginone is a low molecular weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1(I) and matrix metalloproteinase 2 (MMP-2) gene expression. Halofuginone also effectively suppresses tumor progression and metastasis...	PROLYL-TRNA SYNTHETASE (PRORS) (Toxoplasma gondii (strain atcc 50611 / me49))	HGTP_anticodon ProRS-C_1 tRNA-synt_2b	5XIQ_A_HFGA1002	Details
6aog	CP6	Pyrimethamine (DB00205)	Pyrimethamine is an antiparasitic drug used in the prevention and treatment of toxoplasmosis and malaria.	BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (Toxoplasma gondii)	Thymidylat_synt	6AOG_A_CP6A704	Details
PDB	Ligand	Drug	Indication	Macromolecule/ Organism	Pfam	Binding_Interfaces (View)	Details

[["1upf","URF","Fluorouracil (DB00544)","Toxoplasma gondii","URACIL PHOSPHORIBOSYLTRANSFERASE","UPRTase"],["2o2s","TCL","Triclosan (DB08604)","Toxoplasma gondii","ENOYL-ACYL CARRIER REDUCTASE","adh_short_C2"],["4ifg","1E8","Ibrutinib (DB09053)","Toxoplasma gondii","CALMODULIN-DOMAIN PROTEIN KINASE 1","EF-hand_7;Pkinase"],["5xiq","HFG","Halofuginone (DB04866)","Toxoplasma gondii (strain atcc 50611 \/ me49)","PROLYL-TRNA SYNTHETASE (PRORS)","HGTP_anticodon;ProRS-C_1;tRNA-synt_2b"],["6aog","CP6","Pyrimethamine (DB00205)","Toxoplasma gondii","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","Thymidylat_synt"]]