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| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
|---|---|---|---|---|---|---|---|
| 1c8l | CFF | Caffeine (DB00201) | Caffeine is a stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth. | PROTEIN (GLYCOGEN PHOSPHORYLASE) (Oryctolagus cuniculus) | Phosphorylase | ||
| 1nr6 | DIF | Diclofenac (DB00586) | Diclofenac is an NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis. | CYTOCHROME P450 2C5 (Oryctolagus cuniculus) | p450 | ||
| 1q13 | TES | Testosterone (DB00624) | Testosterone is a hormone used to treat hypogonadism, breast carcinoma in women, or the vasomotor symptoms of menopause. | PROSTAGLANDIN-E2 9-REDUCTASE (Oryctolagus cuniculus) | Aldo_ket_red | ||
| 2bdm | TMI | Bifonazole (DB04794) | Bifonazole is an azole antifungal drug used to treat fungal skin infections, such as dermatomycosis. | CYTOCHROME P450 2B4 (Oryctolagus cuniculus) | p450 | ||
| 2hmp | 211 | Trolamine (DB13747) | Trolamine, which is also referred to as triethanolamine (TEA), is a tertiary amine and a triol. It is a bifunctional compound that exhibits both properties of alcohols and amines. Trolamine... | ACTIN, ALPHA SKELETAL MUSCLE (Oryctolagus cuniculus) | Actin | ||
| 3bcr | AZZ | Zidovudine (DB00495) | Zidovudine is a dideoxynucleoside used in the treatment of HIV infection. | GLYCOGEN PHOSPHORYLASE, MUSCLE FORM (Oryctolagus cuniculus) | Phosphorylase | ||
| 3kw4 | TIC | Ticlopidine (DB00208) | Ticlopidine is a platelet aggregation inhibitor used in the prevention of conditions associated with thrombi, such as stroke and transient ischemic attacks (TIA). | CYTOCHROME P450 2B4 (Oryctolagus cuniculus) | p450 | ||
| 3tmz | 06X | Amlodipine (DB00381) | Amlodipine is a calcium channel blocker used to treat hypertension and angina. | CYTOCHROME P450 2B4 (Oryctolagus cuniculus) | p450 | ||
| 4h1n | CGE | Clopidogrel (DB00758) | Clopidogrel is an antiplatelet agent used to prevent blood clots in peripheral vascular disease, coronary artery disease, and cerebrovascular disease. | CYTOCHROME P450 2B4 (Oryctolagus cuniculus) | p450 | ||
| 4jlt | 8PR | Paroxetine (DB00715) | Paroxetine is a selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder. | CYTOCHROME P450 2B4 (Oryctolagus cuniculus) | p450 | ||
| 4po0 | NPS | Naproxen (DB00788) | Naproxen is an NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain. | SERUM ALBUMIN (Oryctolagus cuniculus) | Serum_albumin | ||
| 6jp5 | C5U | Nifedipine (DB01115) | Nifedipine is a dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension. | VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1S (Oryctolagus cuniculus) | CAC1F_CCa_chan_IQGPHHIon_trans | ||
| 6jpb | C9F | Diltiazem (DB00343) | Diltiazem is a calcium channel blocker used to treat hypertension and to manage chronic stable angina. | VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1S (Oryctolagus cuniculus) | CAC1F_CCa_chan_IQGPHHIon_trans | ||
| 6ock | 9KL | Dexketoprofen (DB09214) | Dexketoprofen is an NSAID that is the R(-)-enantiomer of racemic ketoprofen with analgesic and anti-inflammatory properties used for the treatment of mild to moderate pain. | SERUM ALBUMIN (Oryctolagus cuniculus) | Serum_albumin | ||
| 7jpx | 6UB | Levamlodipine (DB09237) | Levamlodipine is a calcium channel blocker used to treat hypertension. | VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1S (Oryctolagus cuniculus) | CAC1F_CCa_chan_IQGPHHIon_trans | ||
| 7jur | QOM | Trametinib (DB08911) | Trametinib is a kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer. | DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1;KINASE SUPPRESSOR OF RAS 2 (Homo sapiens;oryctolagus cuniculus) | PK_Tyr_Ser-ThrPkinase | ||
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |