Ligand ID: QOM

Drugbank ID:
Trametinib
(DB08911)

Indication:
Trametinib is a kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer.

LIST OF BINDING INTERFACES for query 'DB08911'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
7JUR_C_QOMC402	7jur	QOM	Trametinib (DB08911)	Homo sapiens; oryctolagus cuniculus	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1; KINASE SUPPRESSOR OF RAS 2	PK_Tyr_Ser-Thr Pkinase	17	LYS C  97 LEU C 118 VAL C 127 ILE C 141 MET C 143 HIS C 188 ARG C 189 ASP C 190 ASP C 208 PHE C 209 GLY C 210 VAL C 211 SER C 212 LEU C 215 ILE C 216 ARG C 234 PRO B 878	QOM C 402		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["7JUR_C_QOMC402","7jur","QOM","Trametinib (DB08911)","Homo sapiens;oryctolagus cuniculus","DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1;KINASE SUPPRESSOR OF RAS 2","PK_Tyr_Ser-Thr;Pkinase",17,"LYS C 97;LEU C 118;VAL C 127;ILE C 141;MET C 143;HIS C 188;ARG C 189;ASP C 190;ASP C 208;PHE C 209;GLY C 210;VAL C 211;SER C 212;LEU C 215;ILE C 216;ARG C 234;PRO B 878","QOM C 402\r"]]