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| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
|---|---|---|---|---|---|---|---|
| 2o73 | 2AL | Allantoin (DB11100) | Allantoin is an ingredient used in skin care products to relieve irritation and protect minor cuts, scrapes, and burns. | OHCU DECARBOXYLASE (Danio rerio) | OHCU_decarbox | ||
| 2qo4 | CHD | Cholic acid (DB02659) | Cholic Acid is a bile acid used for the treatment of bile acid synthesis disorders due to single enzyme defects and as an adjunctive treatment of peroxisomal disorders with disrupted liver function. | LIVER-BASIC FATTY ACID BINDING PROTEIN (Danio rerio) | Lipocalin_7 | ||
| 3elz | CHD | Cholic acid (DB02659) | Cholic Acid is a bile acid used for the treatment of bile acid synthesis disorders due to single enzyme defects and as an adjunctive treatment of peroxisomal disorders with disrupted liver function. | ILEAL BILE ACID-BINDING PROTEIN (Danio rerio) | NA | ||
| 3q1e | T44 | Levothyroxine (DB00451) | Levothyroxine is a synthetic T4 hormone used to treat hypothyroidism that can be used along with surgery and radioiodine therapy to manage thyrotropin-dependent well-differentiated thyroid cancer. | 5-HYDROXYISOURATE HYDROLASE (Danio rerio) | Transthyretin | ||
| 4r20 | AER | Abiraterone (DB05812) | Abiraterone is an antiandrogen used in the treatment of prostate cancer. | CYTOCHROME P450 FAMILY 17 POLYPEPTIDE 2 (Danio rerio) | p450 | ||
| 4r21 | STR | Progesterone (DB00396) | Progesterone is a hormone used for a variety of functions, including contraception, control of abnormal uterine bleeding, maintenance of pregnancy, and prevention of endometrial hyperplasia. | CYTOCHROME P450 FAMILY 17 POLYPEPTIDE 2 (Danio rerio) | p450 | ||
| 5eei | SHH | Vorinostat (DB02546) | Vorinostat is a histone deacetylase (HDAC) inhibitor used for the treatment of cutaneous manifestations in patients with progressive, persistent, or recurrent cutaneous T- cell lymphoma (CTCL) following prior systemic therapies. | HDAC6 PROTEIN (Danio rerio) | Hist_deacetyl | ||
| 5een | 5OG | Belinostat (DB05015) | Belinostat is a histone deacetylase (HDAC) inhibitor used for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL). | HDAC6 PROTEIN (Danio rerio) | Hist_deacetyl | ||
| 5ef8 | LBH | Panobinostat (DB06603) | Panobinostat is a non-selective histone deacetylase inhibitor used to treat multiple myeloma in combination with other antineoplastic agents. | HDAC6 PROTEIN (Danio rerio) | Hist_deacetyl | ||
| 6b82 | AER | Abiraterone (DB05812) | Abiraterone is an antiandrogen used in the treatment of prostate cancer. | CYTOCHROME P450, FAMILY 17, SUBFAMILY A, POLYPEPTIDE 1 (Danio rerio) | p450 | ||
| 6plx | ABU | Gamma-aminobutyric acid (DB02530) | The most common inhibitory neurotransmitter in the central nervous system. | GLYCINE RECEPTOR SUBUNIT ALPHAZ1 (Danio rerio) | Neur_chan_LBDNeur_chan_memb | ||
| 6vm3 | IVM | Ivermectin (DB00602) | Ivermectin is an anti parasite medication used to treat head lice, onchocerciasis, strongyloidiasis, ascariasis, trichuriasis, and enterobiasis. | GLYCINE RECEPTOR SUBUNIT ALPHAZ1 (Danio rerio) | Neur_chan_LBDNeur_chan_memb | ||
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |