To provide examples on how the web server can be used for protein binding site prediction, we illustrate some case studies used to analyse protein-drug interactions in different perspectives.
CASE STUDIES
Case study 1: Exploring a known example of repurposed drug: Sildenafil
Case study 2: Exploring an example of approved drug with multiple targets: Acarbose
Case study 3: Exploring approved drug molecules related to specific indication: Diabetes
Case study 4: Exploring an example of protein target for multiple drugs: 7tm_I
Case study 5: Prediction of drug binding sites in a protein from structural similarity searches: ACK1 protein
Case study 6: Prediction of drug binding site for an uncharacterized protein
To provide templates on how the web server can be accessed using Python programming language. Required packages: sys, os, re, requests, ast, optparse.
template_drreposer.py