
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
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PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
---|---|---|---|---|---|---|---|
1oxr | AIN | Acetylsalicylic acid (DB00945) | Aspirin is a salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events. | PHOSPHOLIPASE A2 ISOFORM 3 (Naja sagittifera) | Phospholip_A2_1 | ||
1q7a | OPB | Oxyphenbutazone (DB03585) | Oxyphenbutazone is a nonsteroidal anti-inflammatory drug (NSAID) no longer commonly used for the symptomatic relief of musculoskeletal pain. | PHOSPHOLIPASE A2 VRV-PL-VIIIA (Daboia russellii pulchella) | Phospholip_A2_1 | ||
1sv9 | DIF | Diclofenac (DB00586) | Diclofenac is an NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis. | PHOSPHOLIPASE A2 (Daboia russellii russellii) | Phospholip_A2_1 | ||
1sxk | BHA | Aminosalicylic acid (DB00233) | Aminosalicylic acid is an aminosalicylate drug used to induce remission in ulcerative colitis. | PHOSPHOLIPASE A2 VRV-PL-VIIIA (Daboia russellii russellii) | Phospholip_A2_1 | ||
1tgm | AIN | Acetylsalicylic acid (DB00945) | Aspirin is a salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events. | PHOSPHOLIPASE A2 (Daboia russellii russellii) | Phospholip_A2_1 | ||
1th6 | OIN | Atropine (DB00572) | Atropine is a muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs. | PHOSPHOLIPASE A2 (Daboia russellii russellii) | Phospholip_A2_1 | ||
1zr8 | AJM | Ajmaline (DB01426) | Ajmaline is an antiarrhythmic used to manage a variety of forms of tachycardias. | PHOSPHOLIPASE A2 VRV-PL-VIIIA (Daboia russellii pulchella) | Phospholip_A2_1 | ||
1zwp | NIM | Nimesulide (DB04743) | Nimesulide is a cyclooxygenase 2 inhibitor used to treat acute pain and primary dysmenorrhea. | PHOSPHOLIPASE A2 VRV-PL-VIIIA (Daboia russellii pulchella) | Phospholip_A2_1 | ||
2azy | CHD | Cholic acid (DB02659) | Cholic Acid is a bile acid used for the treatment of bile acid synthesis disorders due to single enzyme defects and as an adjunctive treatment of peroxisomal disorders with disrupted liver function. | PHOSPHOLIPASE A2, MAJOR ISOENZYME (Sus scrofa) | Phospholip_A2_1 | ||
2dpz | TYL | Acetaminophen (DB00316) | Acetaminophen is an analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent. | PHOSPHOLIPASE A2 VRV-PL-VIIIA (Daboia russellii pulchella) | Phospholip_A2_1 | ||
2pws | IBP | Dexibuprofen (DB09213) | Dexibuprofen is a pharmacologically active enantiomer of racemic ibuprofen (NSAID) used to treat pain and inflammation. | PHOSPHOLIPASE A2 VRV-PL-VIIIA (Daboia russellii pulchella) | Phospholip_A2_1 | ||
2qu9 | EUG | Isoeugenol (DB14188) | Isoeugenol is a commonly used fragrance added to many commercially available products, and occurs naturally in the essential oils of plants such as ylang-ylang. It is also a significant dermatologic... | PHOSPHOLIPASE A2 VRV-PL-VIIIA (Daboia russellii pulchella) | Phospholip_A2_1 | ||
2qvd | BER | Berberine (DB04115) | An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal... | PHOSPHOLIPASE A2 VRV-PL-VIIIA (Daboia russellii pulchella) | Phospholip_A2_1 | ||
2wq5 | MIY | Minocycline (DB01017) | Minocycline is a tetracycline analog used to treat a wide variety of infections in the body. | PHOSPHOLIPASE A2, ACIDIC (Naja naja) | Phospholip_A2_1 | ||
3fo7 | IMN | Indomethacin (DB00328) | Indomethacin is a nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants. | PHOSPHOLIPASE A2 VRV-PL-VIIIA (Daboia russelli pulchella) | Phospholip_A2_1 | ||
3osh | OIN | Atropine (DB00572) | Atropine is a muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs. | PHOSPHOLIPASE A2 ISOFORM 3 (Naja sagittifera) | Phospholip_A2_1 | ||
4dbk | BER | Berberine (DB04115) | An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal... | PHOSPHOLIPASE A2, MAJOR ISOENZYME (Sus scrofa) | Phospholip_A2_1 | ||
4ntx | AMR | Amiloride (DB00594) | Amiloride is a pyrizine compound used to treat hypertension and congestive heart failure. | ACID-SENSING ION CHANNEL 1;BASIC PHOSPHOLIPASE A2 HOMOLOG TX-BETA (Gallus gallus;micrurus tener tener) | ASCPhospholip_A2_1 | ||
6mqf | AIN | Acetylsalicylic acid (DB00945) | Aspirin is a salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events. | BASIC PHOSPHOLIPASE A2 HOMOLOG 2 (Bothrops moojeni) | Phospholip_A2_1 | ||
PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |