LIST OF BINDING INTERFACES for query 'PHOSPHATIDYLINOSITOL 4' in category 'PROTEIN NAME'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
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PDB	Ligand	Drug	Indication	Macromolecule/ Organism	Pfam	Binding_Interfaces (View)	Details
4jps	1LT	Alpelisib (DB12015)	Alpelisib is a phosphatidylinositol 3-kinase (PI3K) inhibitor with potent antitumor activity. It works by selectively inhibiting class I PI3K p110α , which is the catalytic subunit of PI3K, a lipid...	PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM (Homo sapiens)	PI3K_C2 PI3K_p85B PI3K_rbd PI3Ka PI3_PI4_kinase	4JPS_A_1LTA1102	Details
4xe0	40L	Idelalisib (DB09054)	Idelalisib is an antineoplastic kinase inhibitor used to treat chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL).	PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM (Mus musculus)	PI3K_C2 PI3K_rbd PI3Ka PI3_PI4_kinase	4XE0_A_40LA1101	Details
5swr	SAL	Salicylic acid (DB00936)	Salicylic acid is an acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts.	PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT ALPHA; PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM (Homo sapiens)	PI3K_C2 PI3K_P85_iSH2 PI3K_p85B PI3K_rbd PI3Ka PI3_PI4_kinase SH2	5SWR_B_SALB701	Details
5sxc	URF	Fluorouracil (DB00544)	Fluorouracil is a pyrimidine analog used to treat basal cell carcinomas, and as an injection in palliative cancer treatment.	PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM (Homo sapiens)	PI3K_C2 PI3K_p85B PI3K_rbd PI3Ka PI3_PI4_kinase	5SXC_A_URFA1101	Details
PDB	Ligand	Drug	Indication	Macromolecule/ Organism	Pfam	Binding_Interfaces (View)	Details

[["4jps","1LT","Alpelisib (DB12015)","Homo sapiens","PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM","PI3K_C2;PI3K_p85B;PI3K_rbd;PI3Ka;PI3_PI4_kinase"],["4xe0","40L","Idelalisib (DB09054)","Mus musculus","PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM","PI3K_C2;PI3K_rbd;PI3Ka;PI3_PI4_kinase"],["5swr","SAL","Salicylic acid (DB00936)","Homo sapiens","PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT ALPHA;PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM","PI3K_C2;PI3K_P85_iSH2;PI3K_p85B;PI3K_rbd;PI3Ka;PI3_PI4_kinase;SH2"],["5sxc","URF","Fluorouracil (DB00544)","Homo sapiens","PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM","PI3K_C2;PI3K_p85B;PI3K_rbd;PI3Ka;PI3_PI4_kinase"]]