Ligand ID: 40L

Drugbank ID:
Idelalisib
(DB09054)

Indication:
Idelalisib is an antineoplastic kinase inhibitor used to treat chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL).

LIST OF BINDING INTERFACES for query 'DB09054'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
4XE0_A_40LA1101	4xe0	40L	Idelalisib (DB09054)	Mus musculus	PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM	PI3K_C2 PI3K_rbd PI3Ka PI3_PI4_kinase	19	THR A 750 PHE A 751 MET A 752 PRO A 758 LEU A 759 TRP A 760 ILE A 777 TYR A 813 ILE A 825 GLU A 826 VAL A 827 VAL A 828 SER A 831 ASP A 832 THR A 833 ASN A 836 MET A 900 ILE A 910 ASP A 911	40L A1101		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["4XE0_A_40LA1101","4xe0","40L","Idelalisib (DB09054)","Mus musculus","PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM","PI3K_C2;PI3K_rbd;PI3Ka;PI3_PI4_kinase",19,"THR A 750;PHE A 751;MET A 752;PRO A 758;LEU A 759;TRP A 760;ILE A 777;TYR A 813;ILE A 825;GLU A 826;VAL A 827;VAL A 828;SER A 831;ASP A 832;THR A 833;ASN A 836;MET A 900;ILE A 910;ASP A 911","40L A1101\r"]]