
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)
PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
---|---|---|---|---|---|---|---|
3ld6 | KKK | Ketoconazole (DB01026) | Ketoconazole is a broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections. | LANOSTEROL 14-ALPHA DEMETHYLASE (Homo sapiens) | p450 | ||
4ze1 | X2N | Posaconazole (DB01263) | Posaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients. | LANOSTEROL 14-ALPHA DEMETHYLASE (Saccharomyces cerevisiae (strain yjm789)) | p450 | ||
5esg | 1YN | Itraconazole (DB01167) | Itraconazole is an antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis. | LANOSTEROL 14-ALPHA DEMETHYLASE (Saccharomyces cerevisiae (strain yjm789)) | p450 | ||
5esm | TPF | Fluconazole (DB00196) | Fluconazole is a triazole antifungal used to treat various fungal infections including candidiasis. | LANOSTEROL 14-ALPHA DEMETHYLASE (Saccharomyces cerevisiae (strain yjm789)) | p450 | ||
5hs1 | VOR | Voriconazole (DB00582) | Voriconazole is a triazole compound used to treat fungal infections. | LANOSTEROL 14-ALPHA DEMETHYLASE (Saccharomyces cerevisiae) | p450 | ||
5jlc | 1YN | Itraconazole (DB01167) | Itraconazole is an antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis. | LANOSTEROL 14-ALPHA DEMETHYLASE (Candida glabrata (strain atcc 2001 / cbs 138 / jcm 3761 / nbrc 0622 / nrrl y-65)) | p450 | ||
5v5z | 1YN | Itraconazole (DB01167) | Itraconazole is an antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis. | LANOSTEROL 14-ALPHA DEMETHYLASE (Candida albicans (strain sc5314 / atcc mya-2876)) | p450 | ||
PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |