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| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
|---|---|---|---|---|---|---|---|
| 5fsa | X2N | Posaconazole (DB01263) | Posaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients. | CYP51 VARIANT1 (Candida albicans) | p450 | ||
| 5tl8 | X2N | Posaconazole (DB01263) | Posaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients. | PROTEIN CYP51 (Naegleria fowleri) | p450 | ||
| 6ay4 | TPF | Fluconazole (DB00196) | Fluconazole is a triazole antifungal used to treat various fungal infections including candidiasis. | CYP51, STEROL 14ALPHA-DEMETHYLASE (Naegleria fowleri) | p450 | ||
| 6ay6 | VOR | Voriconazole (DB00582) | Voriconazole is a triazole compound used to treat fungal infections. | CYP51, STEROL 14ALPHA-DEMETHYLASE (Naegleria fowleri) | p450 | ||
| 6ayb | KKK | Ketoconazole (DB01026) | Ketoconazole is a broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections. | CYP51, STEROL 14ALPHA-DEMETHYLASE (Naegleria fowleri) | p450 | ||
| 6ayc | 1YN | Itraconazole (DB01167) | Itraconazole is an antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis. | PROTEIN CYP51 (Naegleria fowleri) | p450 | ||
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |