(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
|---|---|---|---|---|---|---|---|
| 1acj | THA | Tacrine (DB00382) | Tacrine is an anticholinesterase drug used for the management of Alzheimer's disease symptoms. | ACETYLCHOLINESTERASE (Torpedo californica) | COesterase | ||
| 1gpk | HUP | Huperzine a (DB04864) | Huperzine A, is a naturally occurring sesquiterpene alkaloid found in the extracts of the firmoss Huperzia serrata. The botanical has been used in China for centuries for the treatment of... | ACETYLCHOLINESTERASE (Torpedo californica) | COesterase | ||
| 1u65 | CP0 | Irinotecan (DB00762) | Irinotecan is an antineoplastic enzyme inhibitor used to treat metastatic carcinoma of the colon or rectum. | ACETYLCHOLINESTERASE (Torpedo californica) | COesterase | ||
| 1w6r | GNT | Galantamine (DB00674) | Galantamine is a cholinesterase inhibitor used to manage mild to moderate dementia associated with Alzheimer's Disease. | ACETYLCHOLINESTERASE (Torpedo californica) | COesterase | ||
| 2ace | ACH | Acetylcholine (DB03128) | Acetylcholine is a parasympathomimetic neurotransmitter used to induce miosis of the iris in seconds after delivery of the lens in cataract surgery, in penetrating keratoplasty, iridectomy and other anterior segment surgery where rapid miosis may be required. | ACETYLCHOLINESTERASE (Torpedo californica) | COesterase | ||
| 2ack | EDR | Edrophonium (DB01010) | Edrophonium is a cholinesterase inhibitor used to diagnose and evaluate myasthenia gravis. | ACETYLCHOLINESTERASE (Torpedo californica) | COesterase | ||
| 2ha2 | SCK | Succinylcholine (DB00202) | Succinylcholine is a depolarizing skeletal muscle relaxant used adjunctly to anesthesia and for skeletal muscle relaxation during intubation, mechanical ventilation, and surgical procedures. | ACETYLCHOLINESTERASE (Mus musculus) | COesterase | ||
| 2ha4 | ACH | Acetylcholine (DB03128) | Acetylcholine is a parasympathomimetic neurotransmitter used to induce miosis of the iris in seconds after delivery of the lens in cataract surgery, in penetrating keratoplasty, iridectomy and other anterior segment surgery where rapid miosis may be required. | ACETYLCHOLINESTERASE (Mus musculus) | COesterase | ||
| 2xud | DME | Decamethonium (DB01245) | Decamethonium is used in anesthesia to cause paralysis. It is a short acting depolarizing muscle relaxant. It is similar to acetylcholine and acts as a partial agonist of the nicotinic... | ACETYLCHOLINESTERASE (Mus musculus) | COesterase | ||
| 4ey5 | HUP | Huperzine a (DB04864) | Huperzine A, is a naturally occurring sesquiterpene alkaloid found in the extracts of the firmoss Huperzia serrata. The botanical has been used in China for centuries for the treatment of... | ACETYLCHOLINESTERASE (Homo sapiens) | COesterase | ||
| 4ey6 | GNT | Galantamine (DB00674) | Galantamine is a cholinesterase inhibitor used to manage mild to moderate dementia associated with Alzheimer's Disease. | ACETYLCHOLINESTERASE (Homo sapiens) | COesterase | ||
| 5e4j | DME | Decamethonium (DB01245) | Decamethonium is used in anesthesia to cause paralysis. It is a short acting depolarizing muscle relaxant. It is similar to acetylcholine and acts as a partial agonist of the nicotinic... | ACETYLCHOLINESTERASE (Torpedo californica) | COesterase | ||
| 5ov9 | CVI | Gentian violet cation (DB00406) | Gentian Violet is an antiseptic violet dye used to prevent various infections, including fungal and bacterial infections. | ACETYLCHOLINESTERASE (Mus musculus) | COesterase | ||
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |