Ligand ID: GNT

Drugbank ID:
Galantamine
(DB00674)

Indication:
Galantamine is a cholinesterase inhibitor used to manage mild to moderate dementia associated with Alzheimer's Disease.

LIST OF BINDING INTERFACES for query 'DB00674'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1W6R_A_GNTA1536	1w6r	GNT	Galantamine (DB00674)	Torpedo californica	ACETYLCHOLINESTERASE	COesterase	17	ASP A  72 TRP A  84 GLY A 117 GLY A 118 GLY A 119 TYR A 121 TYR A 130 GLU A 199 SER A 200 TRP A 233 PHE A 288 PHE A 290 PHE A 330 PHE A 331 TYR A 334 HIS A 440 GLY A 441	GNT A1536		Details
2PH9_A_GNTA301	2ph9	GNT	Galantamine (DB00674)	Aplysia californica	SOLUBLE ACETYLCHOLINE RECEPTOR	Neur_chan_LBD	8	TYR B  55 TYR A  93 ILE B 118 TRP A 147 SER B 167 GLN A 186 TYR A 188 TYR A 195	GNT A 301		Details
4EY6_A_GNTA604	4ey6	GNT	Galantamine (DB00674)	Homo sapiens	ACETYLCHOLINESTERASE	COesterase	17	ASP A  74 TRP A  86 GLY A 120 GLY A 121 GLY A 122 TYR A 124 SER A 125 TYR A 133 GLU A 202 SER A 203 PHE A 295 PHE A 297 TYR A 337 PHE A 338 TYR A 341 HIS A 447 GLY A 448	GNT A 604		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1W6R_A_GNTA1536","1w6r","GNT","Galantamine (DB00674)","Torpedo californica","ACETYLCHOLINESTERASE","COesterase",17,"ASP A 72;TRP A 84;GLY A 117;GLY A 118;GLY A 119;TYR A 121;TYR A 130;GLU A 199;SER A 200;TRP A 233;PHE A 288;PHE A 290;PHE A 330;PHE A 331;TYR A 334;HIS A 440;GLY A 441","GNT A1536\r"],["2PH9_A_GNTA301","2ph9","GNT","Galantamine (DB00674)","Aplysia californica","SOLUBLE ACETYLCHOLINE RECEPTOR","Neur_chan_LBD",8,"TYR B 55;TYR A 93;ILE B 118;TRP A 147;SER B 167;GLN A 186;TYR A 188;TYR A 195","GNT A 301\r"],["4EY6_A_GNTA604","4ey6","GNT","Galantamine (DB00674)","Homo sapiens","ACETYLCHOLINESTERASE","COesterase",17,"ASP A 74;TRP A 86;GLY A 120;GLY A 121;GLY A 122;TYR A 124;SER A 125;TYR A 133;GLU A 202;SER A 203;PHE A 295;PHE A 297;TYR A 337;PHE A 338;TYR A 341;HIS A 447;GLY A 448","GNT A 604\r"]]