Ligand ID: HUP

Drugbank ID:
Huperzine a
(DB04864)

Indication:
Huperzine A, is a naturally occurring sesquiterpene alkaloid found in the extracts of the firmoss Huperzia serrata. The botanical has been used in China for centuries for the treatment of...

LIST OF BINDING INTERFACES for query 'HUP'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1GPK_A_HUPA1540	1gpk	HUP	Huperzine a (DB04864)	Torpedo californica	ACETYLCHOLINESTERASE	COesterase	17	TRP A  84 TYR A 116 GLY A 117 GLY A 118 GLY A 119 TYR A 121 SER A 122 GLY A 123 SER A 124 LEU A 127 TYR A 130 GLU A 199 SER A 200 PHE A 290 PHE A 330 PHE A 331 HIS A 440	HUP A1540		Details
4EY5_A_HUPA604	4ey5	HUP	Huperzine a (DB04864)	Homo sapiens	ACETYLCHOLINESTERASE	COesterase	18	TRP A  86 TYR A 119 GLY A 120 GLY A 121 GLY A 122 TYR A 124 SER A 125 GLY A 126 ALA A 127 LEU A 130 TYR A 133 GLU A 202 SER A 203 PHE A 297 TYR A 337 PHE A 338 HIS A 447 TYR A 449	HUP A 604		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1GPK_A_HUPA1540","1gpk","HUP","Huperzine a (DB04864)","Torpedo californica","ACETYLCHOLINESTERASE","COesterase",17,"TRP A 84;TYR A 116;GLY A 117;GLY A 118;GLY A 119;TYR A 121;SER A 122;GLY A 123;SER A 124;LEU A 127;TYR A 130;GLU A 199;SER A 200;PHE A 290;PHE A 330;PHE A 331;HIS A 440","HUP A1540\r"],["4EY5_A_HUPA604","4ey5","HUP","Huperzine a (DB04864)","Homo sapiens","ACETYLCHOLINESTERASE","COesterase",18,"TRP A 86;TYR A 119;GLY A 120;GLY A 121;GLY A 122;TYR A 124;SER A 125;GLY A 126;ALA A 127;LEU A 130;TYR A 133;GLU A 202;SER A 203;PHE A 297;TYR A 337;PHE A 338;HIS A 447;TYR A 449","HUP A 604\r"]]