Results: Ligand

Ligand ID: THA

Drugbank ID:
Tacrine
(DB00382)

Indication:
Tacrine is an anticholinesterase drug used for the management of Alzheimer's disease symptoms.

LIST OF BINDING INTERFACES for query 'DB00382'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1ACJ_A_THAA999	1acj	THA	Tacrine (DB00382)	Torpedo californica	ACETYLCHOLINESTERASE	COesterase	13	GLY A 80 TRP A 84 GLY A 117 GLY A 118 TYR A 130 GLU A 199 PHE A 330 TYR A 334 TRP A 432 ILE A 439 HIS A 440 GLY A 441 TYR A 442	THA A 999
1MX1_A_THAA1	1mx1	THA	Tacrine (DB00382)	Homo sapiens	LIVER CARBOXYLESTERASE I	COesterase	18	LEU A1097 PHE A1101 GLY A1142 GLY A1143 GLU A1220 SER A1221 ALA A1222 THR A1252 VAL A1254 LEU A1255 LEU A1304 LEU A1318 LEU A1358 ILE A1359 LEU A1363 MET A1364 PHE A1426 HIS A1468	THA A 1
2AOW_A_THAA400	2aow	THA	Tacrine (DB00382)	Homo sapiens	HISTAMINE N-METHYLTRANSFERASE	Methyltransf_23	13	TYR A 15 PHE A 19 PHE A 22 GLU A 28 GLN A 143 TYR A 146 TYR A 147 VAL A 173 TRP A 179 TRP A 183 PHE A 243 GLU A 246 ASN A 283	THA A 400
4BDS_A_THAA701	4bds	THA	Tacrine (DB00382)	Homo sapiens	CHOLINESTERASE	COesterase	15	ASP A 70 GLY A 78 TRP A 82 GLY A 115 GLY A 116 TYR A 128 GLU A 197 SER A 198 ALA A 328 TYR A 332 TRP A 430 MET A 437 HIS A 438 GLY A 439 TYR A 440	THA A 701
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1ACJ_A_THAA999","1acj","THA","Tacrine (DB00382)","Torpedo californica","ACETYLCHOLINESTERASE","COesterase",13,"GLY A  80;TRP A  84;GLY A 117;GLY A 118;TYR A 130;GLU A 199;PHE A 330;TYR A 334;TRP A 432;ILE A 439;HIS A 440;GLY A 441;TYR A 442","THA A 999\r"],["1MX1_A_THAA1","1mx1","THA","Tacrine (DB00382)","Homo sapiens","LIVER CARBOXYLESTERASE I","COesterase",18,"LEU A1097;PHE A1101;GLY A1142;GLY A1143;GLU A1220;SER A1221;ALA A1222;THR A1252;VAL A1254;LEU A1255;LEU A1304;LEU A1318;LEU A1358;ILE A1359;LEU A1363;MET A1364;PHE A1426;HIS A1468","THA A   1\r"],["2AOW_A_THAA400","2aow","THA","Tacrine (DB00382)","Homo sapiens","HISTAMINE N-METHYLTRANSFERASE","Methyltransf_23",13,"TYR A  15;PHE A  19;PHE A  22;GLU A  28;GLN A 143;TYR A 146;TYR A 147;VAL A 173;TRP A 179;TRP A 183;PHE A 243;GLU A 246;ASN A 283","THA A 400\r"],["4BDS_A_THAA701","4bds","THA","Tacrine (DB00382)","Homo sapiens","CHOLINESTERASE","COesterase",15,"ASP A  70;GLY A  78;TRP A  82;GLY A 115;GLY A 116;TYR A 128;GLU A 197;SER A 198;ALA A 328;TYR A 332;TRP A 430;MET A 437;HIS A 438;GLY A 439;TYR A 440","THA A 701\r"]]