LIST OF BINDING INTERFACES for query 'Saccharomyces cerevisiae (strain atcc 204508 / s288c)' in category 'SOURCE ORGANISM'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

PDB	Ligand	Drug	Indication	Macromolecule/ Organism	Pfam	Binding_Interfaces (View)	Details
4pd4	AOQ	Atovaquone (DB01117)	Atovaquone is an antimicrobial indicated for the prevention and treatment of Pneumocystis jirovecii pneumonia (PCP) and for the prevention and treatment of Plasmodium falciparum malaria.	CYTOCHROME B (Mus musculus; saccharomyces cerevisiae (strain atcc 204508 / s288c))	Cytochrom_B_C Cytochrome_B	4PD4_C_AOQC4003	Details
5d0s	3BV	Carfilzomib (DB08889)	Carfilzomib is a proteasome inhibitor used either alone or in conjunction with a chemotherapy regimen to treat patients with relapsed or refractory multiple myeloma.	PROTEASOME SUBUNIT BETA TYPE-2; PROTEASOME SUBUNIT BETA TYPE-3 (Saccharomyces cerevisiae (strain atcc 204508 / s288c))	Pr_beta_C Proteasome	5D0S_H_3BVH301  5D0S_K_3BVK301  5D0S_N_3BVN201	Details
5d0s	3BV	Carfilzomib (DB08889)	Carfilzomib is a proteasome inhibitor used either alone or in conjunction with a chemotherapy regimen to treat patients with relapsed or refractory multiple myeloma.	PROTEASOME SUBUNIT BETA TYPE-5; PROTEASOME SUBUNIT BETA TYPE-6 (Saccharomyces cerevisiae (strain atcc 204508 / s288c))	Proteasome	5D0S_H_3BVH301  5D0S_K_3BVK301  5D0S_N_3BVN201	Details
5d0s	3BV	Carfilzomib (DB08889)	Carfilzomib is a proteasome inhibitor used either alone or in conjunction with a chemotherapy regimen to treat patients with relapsed or refractory multiple myeloma.	PROTEASOME SUBUNIT BETA TYPE-1; PROTEASOME SUBUNIT BETA TYPE-2 (Saccharomyces cerevisiae (strain atcc 204508 / s288c))	Pr_beta_C	5D0S_H_3BVH301  5D0S_K_3BVK301  5D0S_N_3BVN201	Details
5l5e	3BV	Carfilzomib (DB08889)	Carfilzomib is a proteasome inhibitor used either alone or in conjunction with a chemotherapy regimen to treat patients with relapsed or refractory multiple myeloma.	PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6; PROTEASOME SUBUNIT BETA TYPE-8,PROTEASOME SUBUNIT BETA TYPE-5 (Saccharomyces cerevisiae (strain atcc 204508 / s288c); homo sapiens; saccharomyces cerevisiae)	Proteasome	5L5E_K_3BVK301	Details
5l5f	BO2	Bortezomib (DB00188)	Bortezomib is a proteasome inhibitor used to treat multiple myeloma in patients who have not been successfully treated with at least two previous therapies.	PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6; PROTEASOME SUBUNIT BETA TYPE-8,PROTEASOME SUBUNIT BETA TYPE-5 (Saccharomyces cerevisiae (strain atcc 204508 / s288c); homo sapiens; saccharomyces cerevisiae)	Proteasome	5L5F_K_BO2K301	Details
5l5y	3BV	Carfilzomib (DB08889)	Carfilzomib is a proteasome inhibitor used either alone or in conjunction with a chemotherapy regimen to treat patients with relapsed or refractory multiple myeloma.	PROTEASOME SUBUNIT BETA TYPE-5,PROTEASOME SUBUNIT BETA TYPE-5; PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6 (Homo sapiens; saccharomyces cerevisiae (strain atcc 204508 / s288c); saccharomyces cerevisiae)	Proteasome	5L5Y_K_3BVK301	Details
5l5z	BO2	Bortezomib (DB00188)	Bortezomib is a proteasome inhibitor used to treat multiple myeloma in patients who have not been successfully treated with at least two previous therapies.	PROTEASOME SUBUNIT BETA TYPE-5,PROTEASOME SUBUNIT BETA TYPE-5; PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6 (Homo sapiens; saccharomyces cerevisiae (strain atcc 204508 / s288c); saccharomyces cerevisiae)	Proteasome	5L5Z_K_BO2K301	Details
5w3j	TA1	Paclitaxel (DB01229)	Paclitaxel is a taxoid chemotherapeutic agent used as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast and lung cancer.	TUBULIN BETA CHAIN (Saccharomyces cerevisiae (strain atcc 204508 / s288c))	Tubulin Tubulin_C	5W3J_B_TA1B502	Details
5ys0	ERG	Ergosterol (DB04038)	A steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably AZOLES, and because when it is present in SKIN of animals, ULTRAVIOLET RAYS...	MEMBRANE-ANCHORED LIPID-BINDING PROTEIN YSP2 (Saccharomyces cerevisiae (strain atcc 204508 / s288c))	VASt	5YS0_A_ERGA1301	Details
6r4l	ERG	Ergosterol (DB04038)	A steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably AZOLES, and because when it is present in SKIN of animals, ULTRAVIOLET RAYS...	NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1-RELATED PROTEIN 1 (Saccharomyces cerevisiae (strain atcc 204508 / s288c))	NPC1_N Patched	6R4L_A_ERGA1201	Details
6r4n	ERG	Ergosterol (DB04038)	A steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably AZOLES, and because when it is present in SKIN of animals, ULTRAVIOLET RAYS...	PHOSPHATIDYLGLYCEROL/PHOSPHATIDYLINOSITOL TRANSFER PROTEIN (Saccharomyces cerevisiae (strain atcc 204508 / s288c))	E1_DerP2_DerF2	6R4N_A_ERGA302	Details
PDB	Ligand	Drug	Indication	Macromolecule/ Organism	Pfam	Binding_Interfaces (View)	Details

[["4pd4","AOQ","Atovaquone (DB01117)","Mus musculus;saccharomyces cerevisiae (strain atcc 204508 \/ s288c)","CYTOCHROME B","Cytochrom_B_C;Cytochrome_B"],["5d0s","3BV","Carfilzomib (DB08889)","Saccharomyces cerevisiae (strain atcc 204508 \/ s288c)","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-3","Pr_beta_C;Proteasome"],["5d0s","3BV","Carfilzomib (DB08889)","Saccharomyces cerevisiae (strain atcc 204508 \/ s288c)","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","Proteasome"],["5d0s","3BV","Carfilzomib (DB08889)","Saccharomyces cerevisiae (strain atcc 204508 \/ s288c)","PROTEASOME SUBUNIT BETA TYPE-1;PROTEASOME SUBUNIT BETA TYPE-2","Pr_beta_C"],["5l5e","3BV","Carfilzomib (DB08889)","Saccharomyces cerevisiae (strain atcc 204508 \/ s288c);homo sapiens;saccharomyces cerevisiae","PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6;PROTEASOME SUBUNIT BETA TYPE-8,PROTEASOME SUBUNIT BETA TYPE-5","Proteasome"],["5l5f","BO2","Bortezomib (DB00188)","Saccharomyces cerevisiae (strain atcc 204508 \/ s288c);homo sapiens;saccharomyces cerevisiae","PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6;PROTEASOME SUBUNIT BETA TYPE-8,PROTEASOME SUBUNIT BETA TYPE-5","Proteasome"],["5l5y","3BV","Carfilzomib (DB08889)","Homo sapiens;saccharomyces cerevisiae (strain atcc 204508 \/ s288c);saccharomyces cerevisiae","PROTEASOME SUBUNIT BETA TYPE-5,PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6","Proteasome"],["5l5z","BO2","Bortezomib (DB00188)","Homo sapiens;saccharomyces cerevisiae (strain atcc 204508 \/ s288c);saccharomyces cerevisiae","PROTEASOME SUBUNIT BETA TYPE-5,PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6","Proteasome"],["5w3j","TA1","Paclitaxel (DB01229)","Saccharomyces cerevisiae (strain atcc 204508 \/ s288c)","TUBULIN BETA CHAIN","Tubulin;Tubulin_C"],["5ys0","ERG","Ergosterol (DB04038)","Saccharomyces cerevisiae (strain atcc 204508 \/ s288c)","MEMBRANE-ANCHORED LIPID-BINDING PROTEIN YSP2","VASt"],["6r4l","ERG","Ergosterol (DB04038)","Saccharomyces cerevisiae (strain atcc 204508 \/ s288c)","NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1-RELATED PROTEIN 1","NPC1_N;Patched"],["6r4n","ERG","Ergosterol (DB04038)","Saccharomyces cerevisiae (strain atcc 204508 \/ s288c)","PHOSPHATIDYLGLYCEROL\/PHOSPHATIDYLINOSITOL TRANSFER PROTEIN","E1_DerP2_DerF2"]]