
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
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PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
---|---|---|---|---|---|---|---|
2bl9 | CP6 | Pyrimethamine (DB00205) | Pyrimethamine is an antiparasitic drug used in the prevention and treatment of toxoplasmosis and malaria. | DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (Plasmodium vivax) | DHFR_1 | ||
2pgr | DCF | Pentostatin (DB00552) | Pentostatin is an adenosine deaminase inhibitor used to treat hairy cell leukemia. | ADENOSINE DEAMINASE (Plasmodium vivax) | A_deaminase | ||
3ez3 | ZOL | Zoledronic acid (DB00399) | Zoledronic acid is a bisphosphonate used to treat malignancy associated hypercalcemia, multiple myeloma, and bone metastasis from solid tumors. | FARNESYL PYROPHOSPHATE SYNTHASE, PUTATIVE (Plasmodium vivax) | polyprenyl_synt | ||
3ihz | FK5 | Tacrolimus (DB00864) | Tacrolimus is a calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis. | 70 KDA PEPTIDYLPROLYL ISOMERASE, PUTATIVE (Plasmodium vivax) | FKBP_C | ||
4mwz | CQA | Amodiaquine (DB00613) | Amodiaquine is an antimalarial drug. | PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE (Plasmodium vivax) | Methyltransf_25 | ||
4rz7 | 1E8 | Ibrutinib (DB09053) | Ibrutinib is an antineoplastic agent used to treat chronic lymphocytic leukemia, mantle cell lymphoma, and Waldenstrom's Macroglobulinemia. | CGMP-DEPENDENT PROTEIN KINASE, PUTATIVE (Plasmodium vivax sal-1) | PkinasecNMP_binding | ||
PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |