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| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
|---|---|---|---|---|---|---|---|
| 2jj8 | AZZ | Zidovudine (DB00495) | Zidovudine is a dideoxynucleoside used in the treatment of HIV infection. | DEOXYNUCLEOSIDE KINASE (Drosophila melanogaster) | NA | ||
| 2vpp | GEO | Gemcitabine (DB00441) | Gemcitabine is a nucleoside metabolic inhibitor used as adjunct therapy in the treatment of certain types of ovarian cancer, non-small cell lung carcinoma, metastatic breast cancer, and as a single agent for pancreatic cancer. | DEOXYNUCLEOSIDE KINASE (Drosophila melanogaster) | NA | ||
| 2vqs | BVD | Brivudine (DB03312) | Brivudine is a drug used to treat herpes zoster. | DEOXYNUCLEOSIDE KINASE (Drosophila melanogaster) | NA | ||
| 2x8z | X8Z | Captopril (DB01197) | Captopril is an ACE inhibitor used for the management of essential or renovascular hypertension, congestive heart failure, left ventricular dysfunction following myocardial infarction, and nephropathy. | ANGIOTENSIN CONVERTING ENZYME (Drosophila melanogaster) | Peptidase_M2 | ||
| 2x90 | EAL | Enalaprilat (DB09477) | Enalaprilat is an antihypertensive agent used for the management of hypertension when oral therapy is not practical. | ANGIOTENSIN CONVERTING ENZYME (Drosophila melanogaster) | Peptidase_M2 | ||
| 2x91 | LPR | Lisinopril (DB00722) | Lisinopril is an ACE inhibitor used to treat hypertension, heart failure, and acute myocardial infarction. | ANGIOTENSIN CONVERTING ENZYME (Drosophila melanogaster) | Peptidase_M2 | ||
| 4m48 | 21B | Nortriptyline (DB00540) | Nortriptyline is a tricyclic antidepressant used in the treatment of depression. | TRANSPORTER (Drosophila melanogaster;mus musculus) | SNF | ||
| 4xnx | 41X | Reboxetine (DB00234) | Reboxetine is a drug used for the acute treatment of major depression and for maintenance therapy of depression. | TRANSPORTER (Drosophila melanogaster;mus musculus) | SNF | ||
| 4xp1 | LDP | Dopamine (DB00988) | Dopamine is a catecholamine neurotransmitter used to treat hemodynamic imbalances, poor perfusion of vital organs, low cardiac output, and hypotension. | DOPAMINE TRANSPORTER, ISOFORM B (Drosophila melanogaster;mus musculus) | SNF | ||
| 4xp6 | B40 | Metamfetamine (DB01577) | Metamfetamine is a sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and exogenous obesity. | TRANSPORTER (Drosophila melanogaster;mus musculus) | SNF | ||
| 4xp9 | 1WE | Dextroamphetamine (DB01576) | Dextroamphetamine is a sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. | TRANSPORTER (Drosophila melanogaster;mus musculus) | SNF | ||
| 5g08 | Z80 | Chlorpromazine (DB00477) | Chlorpromazine is a phenothiazine antipsychotic used to treat nausea, vomiting, preoperative anxiety, schizophrenia, bipolar disorder, and severe behavioral problems in children. | FREQUENIN 2 (Drosophila melanogaster) | EF-hand_1EF-hand_7 | ||
| 6dyn | HSM | Histamine (DB05381) | Histamine is an ingredient of topical drugs for the relief of joint pain or muscle aches and pains. | EBONY (Drosophila melanogaster) | NA | ||
| 6dyo | LDP | Dopamine (DB00988) | Dopamine is a catecholamine neurotransmitter used to treat hemodynamic imbalances, poor perfusion of vital organs, low cardiac output, and hypotension. | EBONY (Drosophila melanogaster) | NA | ||
| 6m38 | 29E | Duloxetine (DB00476) | Duloxetine is a serotonin norepinephrine reuptake inhibitor used to treat generalized anxiety disorder, neuropathic pain, osteoarthritis, and stress incontinence. | SODIUM-DEPENDENT DOPAMINE TRANSPORTER (Drosophila melanogaster;mus musculus) | SNF | ||
| 6m3z | F0F | Milnacipran (DB04896) | Milnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of fibromyalgia and a short-term treatment of major depressive disorder. | SODIUM-DEPENDENT DOPAMINE TRANSPORTER (Drosophila melanogaster;mus musculus) | SNF | ||
| 6m47 | F1U | Tramadol (DB00193) | Tramadol is a centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults. | SODIUM-DEPENDENT DOPAMINE TRANSPORTER (Drosophila melanogaster;mus musculus) | SNF | ||
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |