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| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
|---|---|---|---|---|---|---|---|
| 1c3s | SHH | Vorinostat (DB02546) | Vorinostat is a histone deacetylase (HDAC) inhibitor used for the treatment of cutaneous manifestations in patients with progressive, persistent, or recurrent cutaneous T- cell lymphoma (CTCL) following prior systemic therapies. | HDLP (HISTONE DEACETYLASE-LIKE PROTEIN) (Aquifex aeolicus) | Hist_deacetyl | ||
| 2q6h | CXX | Clomipramine (DB01242) | Clomipramine is a tricyclic antidepressant used in the treatment of obsessive-compulsive disorder and disorders with an obsessive-compulsive component, such as depression, schizophrenia, and Tourette’s disorder. | TRANSPORTER (Aquifex aeolicus) | SNF | ||
| 2q72 | IXX | Imipramine (DB00458) | Imipramine is a tricyclic antidepressant indicated for the treatment of depression and to reduce childhood enuresis. | TRANSPORTER (Aquifex aeolicus) | SNF | ||
| 2qb4 | DSM | Desipramine (DB01151) | Desipramine is a tricyclic antidepressant used in the treatment of depression. | TRANSPORTER (Aquifex aeolicus) | SNF | ||
| 3gwu | SRE | Sertraline (DB01104) | Sertraline is a selective serotonin reuptake inhibitor (SSRI) indicated to treat major depressive disorder, social anxiety disorder and many other psychiatric conditions. | TRANSPORTER (Aquifex aeolicus) | SNF | ||
| 3hyw | PS9 | Octasulfur (DB09353) | Sulfur is an ingredient of various cosmetic preparations for its keratolytic, antifungal, and antibacterial properties. | SULFIDE-QUINONE REDUCTASE (Aquifex aeolicus) | Pyr_redox_2 | ||
| 4mm4 | 8PR | Paroxetine (DB00715) | Paroxetine is a selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder. | TRANSPORTER (Aquifex aeolicus) | SNF | ||
| 4mm9 | FVX | Fluvoxamine (DB00176) | Fluvoxamine is a selective serotonin-reuptake inhibitor used to treat obsessive-compulsive disorder. | TRANSPORTER (Aquifex aeolicus) | SNF | ||
| 4mmc | 29J | Desvenlafaxine (DB06700) | Desvenlafaxine is an antidepressant agent and SNRI used for the treatment of major depressive disorders in adults. | TRANSPORTER (Aquifex aeolicus) | SNF | ||
| 4mmd | 29E | Duloxetine (DB00476) | Duloxetine is a serotonin norepinephrine reuptake inhibitor used to treat generalized anxiety disorder, neuropathic pain, osteoarthritis, and stress incontinence. | TRANSPORTER (Aquifex aeolicus) | SNF | ||
| 4mme | 29Q | Mazindol (DB00579) | Mazindol is a sympathomimetic used to treat obesity in combination with lifestyle modifications. | TRANSPORTER (Aquifex aeolicus) | SNF | ||
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |