(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
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| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
|---|---|---|---|---|---|---|---|
| 1sa1 | POD | Podofilox (DB01179) | Podofilox is a topical agent used for the treatment of external genital warts and perianal warts. | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN (Rattus norvegicus;bos taurus) | TubulinTubulin_C | ||
| 1tub | TXL | Docetaxel (DB01248) | Docetaxel is a taxoid antineoplastic agent used in the treatment of various cancers, such as locally advanced or metastatic breast cancer, metastatic prostate cancer, gastric adenocarcinoma, and head and neck cancer. | TUBULIN (Sus scrofa) | TubulinTubulin_C | ||
| 5eyp | LOC | Colchicine (DB01394) | Colchicine is an alkaloid used in the symptomatic relief of pain in attacks of gout and to treat the inflammatory symptoms of Familial Mediterranean Fever (FMF). | TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN (Synthetic construct;ovis aries) | TubulinTubulin_C | ||
| 5j2t | VLB | Vinblastine (DB00570) | Vinblastine is a vinca alkaloid used to treat breast cancer, testicular cancer, neuroblastoma, Hodgkin's and non-Hodgkins lymphoma, mycosis fungoides, histiocytosis, and Kaposi's sarcoma. | TUBULIN ALPHA-1B CHAIN;TUBULIN BETA-2B CHAIN (Rattus norvegicus;gallus gallus;bos taurus) | TubulinTubulin_C | ||
| 5jh7 | 6K9 | Eribulin (DB08871) | Eribulin is a microtubule inhibitor used to treat metastatic breast cancer and metastatic or unresectable liposarcoma. | TUBULIN ALPHA-1B CHAIN;TUBULIN BETA-2B CHAIN (Rattus norvegicus;gallus gallus;bos taurus) | TubulinTubulin_C | ||
| 5w3j | TA1 | Paclitaxel (DB01229) | Paclitaxel is a taxoid chemotherapeutic agent used as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast and lung cancer. | TUBULIN BETA CHAIN (Saccharomyces cerevisiae (strain atcc 204508 / s288c)) | TubulinTubulin_C | ||
| 6och | M4Y | Parthenolide (DB13063) | Parthenolide has been used in trials studying the diagnostic of Allergic Contact Dermatitis. | TUBULINYL-TYR CARBOXYPEPTIDASE 1 (Homo sapiens) | NA | ||
| 6wwr | TA1 | Paclitaxel (DB01229) | Paclitaxel is a taxoid chemotherapeutic agent used as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast and lung cancer. | TUBULIN BETA-2B CHAIN (Mus musculus;sus scrofa) | TubulinTubulin_C | ||
| 7daf | GZX | Ixabepilone (DB04845) | Ixabepilone is a microtubule inhibitor administered in combination with capecitabine or alone in the treatment of metastatic or locally advanced breast cancer that has shown inadequate response to taxanes and anthracyclines. | TUBULIN BETA CHAIN (Mus musculus;gallus gallus;sus scrofa) | TubulinTubulin_C | ||
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |