LIST OF BINDING INTERFACES for query 'SERINE/THREONINE-PROTEIN KINASE B-RAF' in category 'PROTEIN NAME'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
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PDB	Ligand	Drug	Indication	Macromolecule/ Organism	Pfam	Binding_Interfaces (View)	Details
4xv2	P06	Dabrafenib (DB08912)	Dabrafenib is a kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer.	SERINE/THREONINE-PROTEIN KINASE B-RAF (Homo sapiens)	NA	4XV2_A_P06A801	Details
5hi2	BAX	Sorafenib (DB00398)	Sorafenib is a kinase inhibitor used in the treatment of unresectable liver carcinoma and advanced renal carcinoma.	SERINE/THREONINE-PROTEIN KINASE B-RAF (Homo sapiens)	PK_Tyr_Ser-Thr	5HI2_A_BAXA801	Details
6p3d	0LI	Ponatinib (DB08901)	Ponatinib is a kinase inhibitor used to treat patients with various types of chronic myeloid leukemia (CML).	SERINE/THREONINE-PROTEIN KINASE B-RAF (Homo sapiens)	PK_Tyr_Ser-Thr	6P3D_A_0LIA1001	Details
PDB	Ligand	Drug	Indication	Macromolecule/ Organism	Pfam	Binding_Interfaces (View)	Details

[["4xv2","P06","Dabrafenib (DB08912)","Homo sapiens","SERINE\/THREONINE-PROTEIN KINASE B-RAF","NA"],["5hi2","BAX","Sorafenib (DB00398)","Homo sapiens","SERINE\/THREONINE-PROTEIN KINASE B-RAF","PK_Tyr_Ser-Thr"],["6p3d","0LI","Ponatinib (DB08901)","Homo sapiens","SERINE\/THREONINE-PROTEIN KINASE B-RAF","PK_Tyr_Ser-Thr"]]