
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
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PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
---|---|---|---|---|---|---|---|
3gcs | BAX | Sorafenib (DB00398) | Sorafenib is a kinase inhibitor used in the treatment of unresectable liver carcinoma and advanced renal carcinoma. | MITOGEN-ACTIVATED PROTEIN KINASE 14 (Homo sapiens) | Pkinase | ||
3hec | STI | Imatinib (DB00619) | Imatinib is a tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors. | MITOGEN-ACTIVATED PROTEIN KINASE 14 (Homo sapiens) | Pkinase | ||
3lfa | 1N1 | Dasatinib (DB01254) | Dasatinib is a tyrosine kinase inhibitor used for the treatment of lymphoblastic or chronic myeloid leukemia with resistance or intolerance to prior therapy. | MITOGEN-ACTIVATED PROTEIN KINASE 14 (Homo sapiens) | Pkinase | ||
5r9p | SFY | Sulfapyridine (DB00891) | Sulfapyridine is a sulfonamide antibiotic used to treat dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum. | MITOGEN-ACTIVATED PROTEIN KINASE 14 (Mus musculus) | Pkinase | ||
6y82 | 308 | Amantadine (DB00915) | Amantadine is a medication used to treat dyskinesia in Parkinson's patients receiving levodopa, as well as extrapyramidal side effects of medications. | MITOGEN-ACTIVATED PROTEIN KINASE 14 (Mus musculus) | Pkinase | ||
PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |