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| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
|---|---|---|---|---|---|---|---|
| 1p5z | AR3 | Cytarabine (DB00987) | Cytarabine is a pyrimidine nucleoside analogue used to treat acute non-lymphocytic leukemia, lymphocytic leukemia, and the blast phase of chronic myelocytic leukemia. | DEOXYCYTIDINE KINASE (Homo sapiens) | dNK | ||
| 2a7q | CFB | Clofarabine (DB00631) | Clofarabine is a purine nucleoside used to treat relapsed or refractory acute lymphoblastic leukemia in patients 1 to 21 years old. | DEOXYCYTIDINE KINASE (Homo sapiens) | dNK | ||
| 2no0 | GEO | Gemcitabine (DB00441) | Gemcitabine is a nucleoside metabolic inhibitor used as adjunct therapy in the treatment of certain types of ovarian cancer, non-small cell lung carcinoma, metastatic breast cancer, and as a single agent for pancreatic cancer. | DEOXYCYTIDINE KINASE (Homo sapiens) | dNK | ||
| 2no6 | ETV | Emtricitabine (DB00879) | Emtricitabine is a nucleoside reverse transcriptase inhibitor used for the treatment and prophylaxis of HIV. | DEOXYCYTIDINE KINASE (Homo sapiens) | dNK | ||
| 2noa | 3TC | Lamivudine (DB00709) | Lamivudine is a reverse transcriptase inhibitor used to treat HIV and hepatitis B infections. | DEOXYCYTIDINE KINASE (Homo sapiens) | dNK | ||
| 2zia | CL9 | Cladribine (DB00242) | Cladribine is a purine antimetabolite used for the management of relapsing forms of Multiple Sclerosis (MS), used in patients who have not responded to or who were unable to tolerate alternative MS drugs. | DEOXYCYTIDINE KINASE (Homo sapiens) | dNK | ||
| 3mjr | AC2 | Acyclovir (DB00787) | Acyclovir is a guanosine analog used to treat herpes simplex, varicella zoster, herpes zoster. | DEOXYCYTIDINE KINASE (Homo sapiens) | dNK | ||
| 3qeo | LLT | Telbivudine (DB01265) | Telbivudine is a thymidine nucleoside analog used for the treatment of chronic hepatitis B with clinical evidence of viral replication or persistent elevations in serum aminotransferases (ALT or AST). | DEOXYCYTIDINE KINASE (Homo sapiens) | dNK | ||
| 5mql | G65 | Masitinib (DB11526) | Masitinib is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in dogs. It has been available in Europe since 2009, under the brand name Masivet. In the... | DEOXYCYTIDINE KINASE (Homo sapiens) | dNK | ||
| 5mqt | STI | Imatinib (DB00619) | Imatinib is a tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors. | DEOXYCYTIDINE KINASE (Homo sapiens) | dNK | ||
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |