Results: Ligand

Ligand ID: AC2

Drugbank ID:
Acyclovir
(DB00787)

Indication:
Acyclovir is a guanosine analog used to treat herpes simplex, varicella zoster, herpes zoster.

LIST OF BINDING INTERFACES for query 'DB00787'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1PWY_E_AC2E290	1pwy	AC2	Acyclovir (DB00787)	Homo sapiens	PURINE NUCLEOSIDE PHOSPHORYLASE	PNP_UDP_1	13	ALA E 116 ALA E 117 GLY E 118 PHE E 200 GLU E 201 VAL E 217 GLY E 218 MET E 219 THR E 242 ASN E 243 VAL E 245 ALA E 255 HIS E 257	AC2 E 290
2KI5_A_AC2A1	2ki5	AC2	Acyclovir (DB00787)	Human herpesvirus 1	PROTEIN (THYMIDINE KINASE)	Herpes_TK	16	HIS A 58 GLU A 83 TRP A 88 ILE A 97 ILE A 100 TYR A 101 MET A 121 GLN A 125 MET A 128 ARG A 163 ALA A 168 TYR A 172 ARG A 176 ARG A 222 GLU A 225 MET A 231	AC2 A 1
3MJR_A_AC2A301	3mjr	AC2	Acyclovir (DB00787)	Homo sapiens	DEOXYCYTIDINE KINASE	dNK	12	ILE A 30 GLU A 53 VAL A 55 TYR A 86 PHE A 96 GLN A 97 ARG A 104 ARG A 128 ASP A 133 PHE A 137 TYR A 204 LEU A 208	AC2 A 301
4DA7_A_AC2A301	4da7	AC2	Acyclovir (DB00787)	Bacillus subtilis	PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE	PNP_UDP_1	15	MET A 64 ARG A 87 SER A 90 CYS A 91 GLY A 92 ALA A 156 GLN A 158 PHE A 159 VAL A 177 GLU A 178 MET A 179 GLU A 180 SER A 202 ASP A 203 VAL A 205	AC2 A 301
5I3C_A_AC2A301	5i3c	AC2	Acyclovir (DB00787)	Escherichia coli o139:h28 (strain e24377a / etec)	PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE	PNP_UDP_1	17	GLY A 20 HIS A 62 GLY A 63 MET A 64 ARG A 87 SER A 90 CYS A 91 GLY A 92 ALA A 156 LEU A 158 PHE A 159 VAL A 178 GLU A 179 MET A 180 GLU A 181 ASP A 204 ILE A 206	AC2 A 301
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1PWY_E_AC2E290","1pwy","AC2","Acyclovir (DB00787)","Homo sapiens","PURINE NUCLEOSIDE PHOSPHORYLASE","PNP_UDP_1",13,"ALA E 116;ALA E 117;GLY E 118;PHE E 200;GLU E 201;VAL E 217;GLY E 218;MET E 219;THR E 242;ASN E 243;VAL E 245;ALA E 255;HIS E 257","AC2 E 290\r"],["2KI5_A_AC2A1","2ki5","AC2","Acyclovir (DB00787)","Human herpesvirus 1","PROTEIN (THYMIDINE KINASE)","Herpes_TK",16,"HIS A  58;GLU A  83;TRP A  88;ILE A  97;ILE A 100;TYR A 101;MET A 121;GLN A 125;MET A 128;ARG A 163;ALA A 168;TYR A 172;ARG A 176;ARG A 222;GLU A 225;MET A 231","AC2 A   1\r"],["3MJR_A_AC2A301","3mjr","AC2","Acyclovir (DB00787)","Homo sapiens","DEOXYCYTIDINE KINASE","dNK",12,"ILE A  30;GLU A  53;VAL A  55;TYR A  86;PHE A  96;GLN A  97;ARG A 104;ARG A 128;ASP A 133;PHE A 137;TYR A 204;LEU A 208","AC2 A 301\r"],["4DA7_A_AC2A301","4da7","AC2","Acyclovir (DB00787)","Bacillus subtilis","PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE","PNP_UDP_1",15,"MET A  64;ARG A  87;SER A  90;CYS A  91;GLY A  92;ALA A 156;GLN A 158;PHE A 159;VAL A 177;GLU A 178;MET A 179;GLU A 180;SER A 202;ASP A 203;VAL A 205","AC2 A 301\r"],["5I3C_A_AC2A301","5i3c","AC2","Acyclovir (DB00787)","Escherichia coli o139:h28 (strain e24377a \/ etec)","PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE","PNP_UDP_1",17,"GLY A  20;HIS A  62;GLY A  63;MET A  64;ARG A  87;SER A  90;CYS A  91;GLY A  92;ALA A 156;LEU A 158;PHE A 159;VAL A 178;GLU A 179;MET A 180;GLU A 181;ASP A 204;ILE A 206","AC2 A 301\r"]]