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| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
|---|---|---|---|---|---|---|---|
| 2geh | NHY | Hydroxyurea (DB01005) | Hydroxyurea is an antimetabolite used to treat sickle cell anemia crisis. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 2hkk | ALE | Epinephrine (DB00668) | Epinephrine is a hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 2pou | I7A | Diclofenamide (DB01144) | Diclofenamide is a carbonic anhydrase inhibitor used for the management of open-angle and secondary glaucoma, as well as acute angle-closure glaucoma in delayed pre-operative setting requiring a reduction in intraocular pressure. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 3hku | TOR | Topiramate (DB00273) | Topiramate is an anticonvulsant drug used in the control of epilepsy and in the prophylaxis and treatment of migraines. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 3hs4 | AZM | Acetazolamide (DB00819) | Acetazolamide is a carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 3ieo | AMJ | Lacosamide (DB06218) | Lacosamide is an antiepileptic drug used to treat partial onset seizures in adults. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 4e3h | HQE | Hydroquinone (DB09526) | Hydroquinone is a topical brightening agent used for the treatment of skin disorders associated with hyperpigmentation including melasma, post-inflammatory hyperpigmentation, sunspots, and freckles. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 4e49 | RCO | Resorcinol (DB11085) | Resorcinol is a 1,3-isomer (or meta-isomer) of benzenediol with the formula C6H4(OH)2. It is used as an antiseptic and disinfectant in topical pharmaceutical products in the treatment of skin disorders... | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 4m2v | BZ1 | Brinzolamide (DB01194) | Brinzolamide is a carbonic anhydrase inhibitor used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 4n16 | CHD | Cholic acid (DB02659) | Cholic Acid is a bile acid used for the treatment of bile acid synthesis disorders due to single enzyme defects and as an adjunctive treatment of peroxisomal disorders with disrupted liver function. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 5c8i | MZM | Methazolamide (DB00703) | Methazolamide is a carbonic anhydrase inhibitor used to treat open angle glaucoma and acute angle closure glaucoma. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 5m78 | SAL | Salicylic acid (DB00936) | Salicylic acid is an acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 6g3q | FO9 | Famotidine (DB00927) | Famotidine is a histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 6rl9 | SAN | Sulfanilamide (DB00259) | Sulfanilamide is a sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 6sg0 | FUN | Furosemide (DB00695) | Furosemide is a loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 7bi5 | 010 | Benzyl alcohol (DB06770) | Benzyl alcohol is an antiparasitic agent used for the topical treatment of head lice infestation in patients 6 months of age and older. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |