LIST OF BINDING INTERFACES for query 'Streptococcus pneumoniae' in category 'SOURCE ORGANISM'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

PDB	Ligand	Drug	Indication	Macromolecule/ Organism	Pfam	Binding_Interfaces (View)	Details
1jyl	CDC	Citicoline (DB12153)	Citicoline is an endogenous intermediate in the formation of phosphatidylcholine from choline which is thought to have neuroprotective effects.	CTP:PHOSPHOCHOLINE CYTIDYLYLTRANSFERASE (Streptococcus pneumoniae)	NTP_transferase	1JYL_A_CDCA1991	Details
2x8m	X8M	Ipratropium (DB00332)	Ipratropium is an anticholinergic drug used in the control of symptoms related to bronchospasm in chronic obstructive pulmonary disease (COPD).	CHOLINE-BINDING PROTEIN F (Streptococcus pneumoniae)	Choline_bind_1 Choline_bind_3	2X8M_A_X8MA1314  2X8M_A_X8MA1316  2X8M_A_X8MA1318	Details
2x8o	OIN	Atropine (DB00572)	Atropine is a muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs.	CHOLINE-BINDING PROTEIN F (Streptococcus pneumoniae)	Choline_bind_1 Choline_bind_3	2X8O_A_OINA1314  2X8O_A_OINA1317	Details
2ya7	ZMR	Zanamivir (DB00558)	Zanamivir is a neuraminidase inhibitor used to treat influenza A and B.	NEURAMINIDASE A (Streptococcus pneumoniae)	BNR_2	2YA7_A_ZMRA1776	Details
3q1l	DHL	Cysteamine (DB00847)	Cysteamine is a cystine depleting agent used to treat the effects of cystinosis.	ASPARTATE BETA-SEMIALDEHYDE DEHYDROGENASE (Streptococcus pneumoniae)	Semialdhyde_dh Semialdhyde_dhC	3Q1L_A_DHLA367	Details
4cu8	DGJ	Migalastat (DB05018)	Migalastat is an alpha-galactosidase A chaperone used for the treatment of Fabry disease in patients with an amenable galactosidase alpha gene (GLA) variant.	GLYCOSIDE HYDROLASE 2 (Streptococcus pneumoniae tigr4)	DUF4982 Glyco_hydro2_C5 Glyco_hydro_2 Glyco_hydro_2_C Glyco_hydro_2_N	4CU8_A_DGJA1985	Details
5oj0	9WT	Cefepime (DB01413)	Cefepime is a fourth-generation cephalosporin antibiotic used in the treatment of various bacterial infections caused by susceptible bacteria, such as pneumonia, urinary tract infections, and skin infections.	PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	PASTA PBP_dimer Transpeptidase	5OJ0_A_9WTA801	Details
PDB	Ligand	Drug	Indication	Macromolecule/ Organism	Pfam	Binding_Interfaces (View)	Details

[["1jyl","CDC","Citicoline (DB12153)","Streptococcus pneumoniae","CTP:PHOSPHOCHOLINE CYTIDYLYLTRANSFERASE","NTP_transferase"],["2x8m","X8M","Ipratropium (DB00332)","Streptococcus pneumoniae","CHOLINE-BINDING PROTEIN F","Choline_bind_1;Choline_bind_3"],["2x8o","OIN","Atropine (DB00572)","Streptococcus pneumoniae","CHOLINE-BINDING PROTEIN F","Choline_bind_1;Choline_bind_3"],["2ya7","ZMR","Zanamivir (DB00558)","Streptococcus pneumoniae","NEURAMINIDASE A","BNR_2"],["3q1l","DHL","Cysteamine (DB00847)","Streptococcus pneumoniae","ASPARTATE BETA-SEMIALDEHYDE DEHYDROGENASE","Semialdhyde_dh;Semialdhyde_dhC"],["4cu8","DGJ","Migalastat (DB05018)","Streptococcus pneumoniae tigr4","GLYCOSIDE HYDROLASE 2","DUF4982;Glyco_hydro2_C5;Glyco_hydro_2;Glyco_hydro_2_C;Glyco_hydro_2_N"],["5oj0","9WT","Cefepime (DB01413)","Streptococcus pneumoniae","PENICILLIN-BINDING PROTEIN 2X","PASTA;PBP_dimer;Transpeptidase"]]