Results: Ligand

Ligand ID: DHL

Drugbank ID:
Cysteamine
(DB00847)

Indication:
Cysteamine is a cystine depleting agent used to treat the effects of cystinosis.

LIST OF BINDING INTERFACES for query 'DB00847'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
2Y8D_A_DHLA3630	2y8d	DHL	Cysteamine (DB00847)	Plasmodium falciparum	ERYTHROCYTE MEMBRANE PROTEIN 1	Duffy_binding	6	VAL A2419 LEU A2477 TYR A2480 THR A2489 GLU A2491 CYS A2493	DHL A3630
3Q1L_A_DHLA367	3q1l	DHL	Cysteamine (DB00847)	Streptococcus pneumoniae	ASPARTATE BETA-SEMIALDEHYDE DEHYDROGENASE	Semialdhyde_dh Semialdhyde_dhC	10	ASN A 127 CYS A 128 SER A 129 GLN A 155 GLY A 159 ALA A 160 ILE A 209 GLU A 220 ARG A 245 HIS A 252	DHL A 367
3SOM_A_DHLA601	3som	DHL	Cysteamine (DB00847)	Homo sapiens	METHYLMALONIC ACIDURIA AND HOMOCYSTINURIA TYPE C PROTEIN	MMACHC	4	PRO A 152 HIS A 180 CYS A 182 VAL A 209	DHL A 601
4CG4_C_DHLC1	4cg4	DHL	Cysteamine (DB00847)	Homo sapiens	PYRIN	PRY SPRY	14	PHE C 636 SER C 638 CYS C 639 ILE C 641 ILE C 674 SER C 675 ARG C 676 LYS C 677 GLY C 678 ASN C 679 MET C 680 THR C 681 LEU C 682 TYR C 688	DHL C 1
4CG4_C_DHLC2	4cg4	DHL	Cysteamine (DB00847)	Homo sapiens	PYRIN	PRY SPRY	6	GLU C 658 ARG C 717 THR C 771 ILE C 772 CYS C 773 PRO C 774	DHL C 2
4PA5_A_DHLA2006	4pa5	DHL	Cysteamine (DB00847)	Bacillus subtilis	PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE	TGL	7	PHE A 69 GLU A 115 CYS A 116 GLN A 183 GLY A 186 GLU A 187 ASN A 188	DHL A2006
5EJ0_A_DHLA701	5ej0	DHL	Cysteamine (DB00847)	Vaccinia virus (strain western reserve)	ENVELOPE PROTEIN H3	NA	11	PHE A 82 SER A 83 GLY A 84 PHE A 85 CYS A 86 MET A 89 CYS A 90 LYS A 95 LEU A 208 SER A 209 PHE A 212	DHL A 701
6XIC_I_DHLI11	6xic	DHL	Cysteamine (DB00847)	Homo sapiens; synthetic construct	PEPTIDE 40; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9	Peptidase_S8	5	TYR I 9 SER B 153 ILE B 154 PRO B 155 ILE B 369	DHL I 11
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["2Y8D_A_DHLA3630","2y8d","DHL","Cysteamine (DB00847)","Plasmodium falciparum","ERYTHROCYTE MEMBRANE PROTEIN 1","Duffy_binding",6,"VAL A2419;LEU A2477;TYR A2480;THR A2489;GLU A2491;CYS A2493","DHL A3630\r"],["3Q1L_A_DHLA367","3q1l","DHL","Cysteamine (DB00847)","Streptococcus pneumoniae","ASPARTATE BETA-SEMIALDEHYDE DEHYDROGENASE","Semialdhyde_dh;Semialdhyde_dhC",10,"ASN A 127;CYS A 128;SER A 129;GLN A 155;GLY A 159;ALA A 160;ILE A 209;GLU A 220;ARG A 245;HIS A 252","DHL A 367\r"],["3SOM_A_DHLA601","3som","DHL","Cysteamine (DB00847)","Homo sapiens","METHYLMALONIC ACIDURIA AND HOMOCYSTINURIA TYPE C PROTEIN","MMACHC",4,"PRO A 152;HIS A 180;CYS A 182;VAL A 209","DHL A 601\r"],["4CG4_C_DHLC1","4cg4","DHL","Cysteamine (DB00847)","Homo sapiens","PYRIN","PRY;SPRY",14,"PHE C 636;SER C 638;CYS C 639;ILE C 641;ILE C 674;SER C 675;ARG C 676;LYS C 677;GLY C 678;ASN C 679;MET C 680;THR C 681;LEU C 682;TYR C 688","DHL C   1\r"],["4CG4_C_DHLC2","4cg4","DHL","Cysteamine (DB00847)","Homo sapiens","PYRIN","PRY;SPRY",6,"GLU C 658;ARG C 717;THR C 771;ILE C 772;CYS C 773;PRO C 774","DHL C   2\r"],["4PA5_A_DHLA2006","4pa5","DHL","Cysteamine (DB00847)","Bacillus subtilis","PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE","TGL",7,"PHE A  69;GLU A 115;CYS A 116;GLN A 183;GLY A 186;GLU A 187;ASN A 188","DHL A2006\r"],["5EJ0_A_DHLA701","5ej0","DHL","Cysteamine (DB00847)","Vaccinia virus (strain western reserve)","ENVELOPE PROTEIN H3","NA",11,"PHE A  82;SER A  83;GLY A  84;PHE A  85;CYS A  86;MET A  89;CYS A  90;LYS A  95;LEU A 208;SER A 209;PHE A 212","DHL A 701\r"],["6XIC_I_DHLI11","6xic","DHL","Cysteamine (DB00847)","Homo sapiens;synthetic construct","PEPTIDE 40;PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Peptidase_S8",5,"TYR I   9;SER B 153;ILE B 154;PRO B 155;ILE B 369","DHL I  11\r"]]