Ligand ID: CDC

Drugbank ID:
Citicoline
(DB12153)

Indication:
Citicoline is an endogenous intermediate in the formation of phosphatidylcholine from choline which is thought to have neuroprotective effects.

LIST OF BINDING INTERFACES for query 'DB12153'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1JYL_A_CDCA1991	1jyl	CDC	Citicoline (DB12153)	Streptococcus pneumoniae	CTP:PHOSPHOCHOLINE CYTIDYLYLTRANSFERASE	NTP_transferase	20	LEU A  11 ALA A  12 ALA A  13 GLY A  14 LYS A  28 ASN A  79 TYR A  82 TYR A  85 ASN A  86 ASN A  87 SER A  90 ASP A 105 ALA A 106 ASP A 107 TRP A 136 LEU A 159 TYR A 190 ASP A 192 GLU A 216 ASP A 218	CDC A1991		Details
3HL4_A_CDCA237	3hl4	CDC	Citicoline (DB12153)	Rattus norvegicus	CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE A	CTP_transf_like	22	ASP A  82 GLY A  83 ILE A  84 PHE A  85 HIS A  89 GLY A  91 HIS A  92 ALA A  95 CYS A 113 LYS A 122 PRO A 150 TRP A 151 HIS A 168 ASP A 169 TYR A 173 VAL A 181 TYR A 182 THR A 194 GLN A 195 ARG A 196 THR A 197 ILE A 200	CDC A 237		Details
4BET_A_CDCA1000	4bet	CDC	Citicoline (DB12153)	Legionella pneumophila	PHOSPHOCHOLINE TRANSFERASE ANKX	Ank_2 Fic	21	PHE A  26 ASP A  28 ARG A  30 PHE A  31 TYR A  41 GLU A  42 ARG A  44 GLU A  45 CYS A  48 PHE A 107 ARG A 113 GLU A 226 ASP A 233 ALA A 234 ASN A 235 GLY A 236 ARG A 237 ASN A 241 PRO A 261 ASN A 262 ASP A 265	CDC A1000		Details
4MVC_A_CDCA401	4mvc	CDC	Citicoline (DB12153)	Rattus norvegicus	CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE A	CTP_transf_like	23	ASP A  82 GLY A  83 ILE A  84 PHE A  85 HIS A  89 GLY A  91 HIS A  92 ALA A  95 CYS A 113 LYS A 122 PRO A 150 TRP A 151 HIS A 168 ASP A 169 TYR A 173 VAL A 181 TYR A 182 THR A 194 GLN A 195 ARG A 196 THR A 197 ILE A 200 SER A 201	CDC A 401		Details
4ZCS_A_CDCA801	4zcs	CDC	Citicoline (DB12153)	Plasmodium falciparum (isolate 3d7)	CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE	CTP_transf_like	21	ASP A 623 GLY A 624 VAL A 625 TYR A 626 HIS A 630 GLY A 632 HIS A 633 GLN A 636 THR A 654 LYS A 663 PRO A 691 TRP A 692 HIS A 709 ASP A 710 TYR A 714 ILE A 740 TYR A 741 THR A 753 GLN A 754 ARG A 755 THR A 756	CDC A 801		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1JYL_A_CDCA1991","1jyl","CDC","Citicoline (DB12153)","Streptococcus pneumoniae","CTP:PHOSPHOCHOLINE CYTIDYLYLTRANSFERASE","NTP_transferase",20,"LEU A 11;ALA A 12;ALA A 13;GLY A 14;LYS A 28;ASN A 79;TYR A 82;TYR A 85;ASN A 86;ASN A 87;SER A 90;ASP A 105;ALA A 106;ASP A 107;TRP A 136;LEU A 159;TYR A 190;ASP A 192;GLU A 216;ASP A 218","CDC A1991\r"],["3HL4_A_CDCA237","3hl4","CDC","Citicoline (DB12153)","Rattus norvegicus","CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE A","CTP_transf_like",22,"ASP A 82;GLY A 83;ILE A 84;PHE A 85;HIS A 89;GLY A 91;HIS A 92;ALA A 95;CYS A 113;LYS A 122;PRO A 150;TRP A 151;HIS A 168;ASP A 169;TYR A 173;VAL A 181;TYR A 182;THR A 194;GLN A 195;ARG A 196;THR A 197;ILE A 200","CDC A 237\r"],["4BET_A_CDCA1000","4bet","CDC","Citicoline (DB12153)","Legionella pneumophila","PHOSPHOCHOLINE TRANSFERASE ANKX","Ank_2;Fic",21,"PHE A 26;ASP A 28;ARG A 30;PHE A 31;TYR A 41;GLU A 42;ARG A 44;GLU A 45;CYS A 48;PHE A 107;ARG A 113;GLU A 226;ASP A 233;ALA A 234;ASN A 235;GLY A 236;ARG A 237;ASN A 241;PRO A 261;ASN A 262;ASP A 265","CDC A1000\r"],["4MVC_A_CDCA401","4mvc","CDC","Citicoline (DB12153)","Rattus norvegicus","CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE A","CTP_transf_like",23,"ASP A 82;GLY A 83;ILE A 84;PHE A 85;HIS A 89;GLY A 91;HIS A 92;ALA A 95;CYS A 113;LYS A 122;PRO A 150;TRP A 151;HIS A 168;ASP A 169;TYR A 173;VAL A 181;TYR A 182;THR A 194;GLN A 195;ARG A 196;THR A 197;ILE A 200;SER A 201","CDC A 401\r"],["4ZCS_A_CDCA801","4zcs","CDC","Citicoline (DB12153)","Plasmodium falciparum (isolate 3d7)","CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE","CTP_transf_like",21,"ASP A 623;GLY A 624;VAL A 625;TYR A 626;HIS A 630;GLY A 632;HIS A 633;GLN A 636;THR A 654;LYS A 663;PRO A 691;TRP A 692;HIS A 709;ASP A 710;TYR A 714;ILE A 740;TYR A 741;THR A 753;GLN A 754;ARG A 755;THR A 756","CDC A 801\r"]]