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| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
|---|---|---|---|---|---|---|---|
| 5rf8 | SFY | Sulfapyridine (DB00891) | Sulfapyridine is a sulfonamide antibiotic used to treat dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum. | 3C-LIKE PROTEINASE (Severe acute respiratory syndrome coronavirus 2) | NA | ||
| 5rsu | OHB | Salicylamide (DB08797) | Salicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. It has similar medicinal uses to aspirin.... | NON-STRUCTURAL PROTEIN 3 (Severe acute respiratory syndrome coronavirus 2) | Macro | ||
| 5rtm | PZA | Pyrazinamide (DB00339) | Pyrazinamide is an antituberculosis agent used as a component of tuberculosis (TB) treatment. | NON-STRUCTURAL PROTEIN 3 (Severe acute respiratory syndrome coronavirus 2) | Macro | ||
| 5rue | BHA | Aminosalicylic acid (DB00233) | Aminosalicylic acid is an aminosalicylate drug used to induce remission in ulcerative colitis. | NON-STRUCTURAL PROTEIN 3 (Severe acute respiratory syndrome coronavirus 2) | Macro | ||
| 5rus | HSM | Histamine (DB05381) | Histamine is an ingredient of topical drugs for the relief of joint pain or muscle aches and pains. | NON-STRUCTURAL PROTEIN 3 (Severe acute respiratory syndrome coronavirus 2) | Macro | ||
| 5rvi | CLW | Chlorzoxazone (DB00356) | Chlorzoxazone is a drug with muscle relaxant properties that is used as an adjunct to physical therapy and analgesics to treat stiffness and pain caused by a variety of musculoskeletal conditions. | NON-STRUCTURAL PROTEIN 3 (Severe acute respiratory syndrome coronavirus 2) | Macro | ||
| 5s3i | W1P | Edaravone (DB12243) | Edaravone is a free radical scavenger used to delay the progression of ALS. | NON-STRUCTURAL PROTEIN 3 (Severe acute respiratory syndrome coronavirus 2) | Macro | ||
| 5s4a | 4AP | Dalfampridine (DB06637) | Dalfampridine is a potassium channel blocker used for the improvement of motor function in patients with multiple sclerosis (MS). | NON-STRUCTURAL PROTEIN 3 (Severe acute respiratory syndrome coronavirus 2) | Macro | ||
| 6wxc | CMU | Tipiracil (DB09343) | Tipiracil is a thymidine phosphorylase inhibitor used as an adjunct treatment of adult patients with certain types of gastric or colorectal malignancies. | URIDYLATE-SPECIFIC ENDORIBONUCLEASE (Severe acute respiratory syndrome coronavirus 2) | CoV_NSP15_CCoV_NSP15_MCoV_NSP15_N | ||
| 7a1u | FUA | Fusidic acid (DB02703) | Fusidic acid is a topical antibacterial agent used to prevent and treat mild to moderate skin infections caused by susceptible bacteria. | 3C-LIKE PROTEINASE (Severe acute respiratory syndrome coronavirus 2) | NA | ||
| 7aqi | QEL | Ifenprodil (DB08954) | N-methyl-D-aspartate (NMDA) receptors (NMDARs) are members of the ionotropic glutamate receptor family, with key roles in brain development and neurological function.[A220118, A220128] NMDARs are heterotetramers that typically involve a dimer... | 3C-LIKE PROTEINASE (Severe acute respiratory syndrome coronavirus 2) | NA | ||
| 7awr | S7W | Tegafur (DB09256) | Tegafur is an antineoplastic agent used in combination with other anticancer medications to treat advanced gastric and colorectal cancers. | 3C-LIKE PROTEINASE (Severe acute respiratory syndrome coronavirus 2) | NA | ||
| 7aww | CLU | Clonidine (DB00575) | Clonidine is an alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines. | 3C-LIKE PROTEINASE (Severe acute respiratory syndrome coronavirus 2) | NA | ||
| 7d7k | CFF | Caffeine (DB00201) | Caffeine is a stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth. | NON-STRUCTURAL PROTEIN 3 (Severe acute respiratory syndrome coronavirus 2) | NA | ||
| 7ju7 | G65 | Masitinib (DB11526) | Masitinib is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in dogs. It has been available in Europe since 2009, under the brand name Masivet. In the... | 3C-LIKE PROTEINASE (Severe acute respiratory syndrome coronavirus 2) | NA | ||
| 7k6d | SV6 | Telaprevir (DB05521) | Telaprevir is an NS3/4A viral protease inhibitor used in combination with other antivirals for the curative treatment of chronic Hepatitis C Virus infections. | 3C-LIKE PROTEINASE (Severe acute respiratory syndrome coronavirus 2) | NA | ||
| 7llf | BO3 | Boric acid (DB11326) | Boric acid, also known as hydrogen borate, is a weak monobasic Lewis acid of boron with the chemical formula H3BO3. Boric acid is typically utilized in industrial processing and manufacturing,... | NON-STRUCTURAL PROTEIN 3 (Severe acute respiratory syndrome coronavirus 2) | NA | ||
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |