Ligand ID: CMU

Drugbank ID:
Tipiracil
(DB09343)

Indication:
Tipiracil is a thymidine phosphorylase inhibitor used as an adjunct treatment of adult patients with certain types of gastric or colorectal malignancies.

LIST OF BINDING INTERFACES for query 'DB09343'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1UOU_A_CMUA1481	1uou	CMU	Tipiracil (DB09343)	Homo sapiens	THYMIDINE PHOSPHORYLASE	Glycos_trans_3N Glycos_transf_3 PYNP_C	17	HIS A 116 SER A 117 THR A 118 GLY A 119 ARG A 146 LEU A 148 THR A 151 GLY A 152 GLY A 153 TYR A 199 ARG A 202 LEU A 213 ILE A 214 SER A 217 ILE A 218 LYS A 221 VAL A 241	CMU A1481		Details
6WXC_A_CMUA401	6wxc	CMU	Tipiracil (DB09343)	Severe acute respiratory syndrome coronavirus 2	URIDYLATE-SPECIFIC ENDORIBONUCLEASE	CoV_NSP15_C CoV_NSP15_M CoV_NSP15_N	9	GLN A 245 HIS A 250 LYS A 290 VAL A 292 CYS A 293 SER A 294 TYR A 343 PRO A 344 LYS A 345	CMU A 401		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1UOU_A_CMUA1481","1uou","CMU","Tipiracil (DB09343)","Homo sapiens","THYMIDINE PHOSPHORYLASE","Glycos_trans_3N;Glycos_transf_3;PYNP_C",17,"HIS A 116;SER A 117;THR A 118;GLY A 119;ARG A 146;LEU A 148;THR A 151;GLY A 152;GLY A 153;TYR A 199;ARG A 202;LEU A 213;ILE A 214;SER A 217;ILE A 218;LYS A 221;VAL A 241","CMU A1481\r"],["6WXC_A_CMUA401","6wxc","CMU","Tipiracil (DB09343)","Severe acute respiratory syndrome coronavirus 2","URIDYLATE-SPECIFIC ENDORIBONUCLEASE","CoV_NSP15_C;CoV_NSP15_M;CoV_NSP15_N",9,"GLN A 245;HIS A 250;LYS A 290;VAL A 292;CYS A 293;SER A 294;TYR A 343;PRO A 344;LYS A 345","CMU A 401\r"]]