Ligand ID: SV6

Drugbank ID:
Telaprevir
(DB05521)

Indication:
Telaprevir is an NS3/4A viral protease inhibitor used in combination with other antivirals for the curative treatment of chronic Hepatitis C Virus infections.

LIST OF BINDING INTERFACES for query 'DB05521'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
3SV6_A_SV6A1	3sv6	SV6	Telaprevir (DB05521)	Hepatitis c virus	NS3 PROTEASE, NS4A PROTEIN	Peptidase_S29	19	GLN A1041 THR A1042 PHE A1043 HIS A1057 ASP A1081 ARG A1123 ILE A1132 LEU A1135 LYS A1136 GLY A1137 SER A1138 SER A1139 PHE A1154 ARG A1155 ALA A1156 ALA A1157 VAL A1158 SER A1159 ASP A1168	SV6 A   1		Details
7K6D_A_SV6A402	7k6d	SV6	Telaprevir (DB05521)	Severe acute respiratory syndrome coronavirus 2	3C-LIKE PROTEINASE	NA	24	THR A  25 THR A  26 LEU A  27 HIS A  41 MET A  49 LEU A 141 ASN A 142 GLY A 143 SER A 144 CYS A 145 HIS A 163 HIS A 164 MET A 165 GLU A 166 LEU A 167 PRO A 168 PHE A 185 VAL A 186 ASP A 187 ARG A 188 GLN A 189 THR A 190 ALA A 191 GLN A 192	SV6 A 402		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["3SV6_A_SV6A1","3sv6","SV6","Telaprevir (DB05521)","Hepatitis c virus","NS3 PROTEASE, NS4A PROTEIN","Peptidase_S29",19,"GLN A1041;THR A1042;PHE A1043;HIS A1057;ASP A1081;ARG A1123;ILE A1132;LEU A1135;LYS A1136;GLY A1137;SER A1138;SER A1139;PHE A1154;ARG A1155;ALA A1156;ALA A1157;VAL A1158;SER A1159;ASP A1168","SV6 A 1\r"],["7K6D_A_SV6A402","7k6d","SV6","Telaprevir (DB05521)","Severe acute respiratory syndrome coronavirus 2","3C-LIKE PROTEINASE","NA",24,"THR A 25;THR A 26;LEU A 27;HIS A 41;MET A 49;LEU A 141;ASN A 142;GLY A 143;SER A 144;CYS A 145;HIS A 163;HIS A 164;MET A 165;GLU A 166;LEU A 167;PRO A 168;PHE A 185;VAL A 186;ASP A 187;ARG A 188;GLN A 189;THR A 190;ALA A 191;GLN A 192","SV6 A 402\r"]]