
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
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PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
---|---|---|---|---|---|---|---|
3kee | 30B | Simeprevir (DB06290) | Simeprevir is a direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4. | GENOME POLYPROTEIN (Hepatitis c virus;synthetic construct) | Peptidase_S29 | ||
3sug | SUE | Grazoprevir (DB11575) | Grazoprevir is an antiviral and NS3/4A protease inhibitor used to treat hepatitis C infections. | NS3 PROTEASE, NS4A PROTEIN (Hepatitis c virus) | Peptidase_S29 | ||
3sv6 | SV6 | Telaprevir (DB05521) | Telaprevir is an NS3/4A viral protease inhibitor used in combination with other antivirals for the curative treatment of chronic Hepatitis C Virus infections. | NS3 PROTEASE, NS4A PROTEIN (Hepatitis c virus) | Peptidase_S29 | ||
4wf8 | 2R9 | Asunaprevir (DB11586) | Asunaprevir is an NS3 protease inhibitor used to treat hepatitis C genotype 1b. | NS3 PROTEIN (Hepatitis c virus) | Peptidase_S29 | ||
6nzt | L9P | Voxilaprevir (DB12026) | Voxilaprevir is a nonstructural protein 3 and 4a protease inhibitor used to treat Hepatitis C infections. | HCV NS3/4A PROTEASE (Hepatitis c virus) | Peptidase_S29 | ||
6p6l | O31 | Glecaprevir (DB13879) | Glecaprevir is a Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C. | NON-STRUCTURAL PROTEIN 4A,SERINE PROTEASE NS3 (Hepatitis c virus genotype 1a (isolate 1)) | Peptidase_S29 | ||
6p6s | O31 | Glecaprevir (DB13879) | Glecaprevir is a Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C. | NON-STRUCTURAL PROTEIN 4A,SERINE PROTEASE NS3 (Hepatitis c virus genotype 3a (isolate nzl1)) | Peptidase_S29 | ||
6p6v | O31 | Glecaprevir (DB13879) | Glecaprevir is a Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C. | NON-STRUCTURAL PROTEIN 4A,SERINE PROTEASE NS3 (Hepatitis c virus genotype 5a (isolate sa13)) | Peptidase_S29 | ||
6p6z | O31 | Glecaprevir (DB13879) | Glecaprevir is a Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C. | NON-STRUCTURAL PROTEIN 4A,SERINE PROTEASE NS3 (Hepatitis c virus genotype 4a (isolate ed43)) | Peptidase_S29 | ||
PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |