Ligand ID: 30B

Drugbank ID:
Simeprevir
(DB06290)

Indication:
Simeprevir is a direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4.

LIST OF BINDING INTERFACES for query '30B'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
3KEE_A_30BA500	3kee	30B	Simeprevir (DB06290)	Hepatitis c virus; synthetic construct	GENOME POLYPROTEIN	Peptidase_S29	23	GLN A  41 SER A  42 PHE A  43 VAL A  55 TYR A  56 HIS A  57 GLY A  58 VAL A  78 ASP A  79 GLN A  80 ASP A  81 VAL A 132 LEU A 135 LYS A 136 GLY A 137 SER A 138 SER A 139 PHE A 154 ARG A 155 ALA A 156 ALA A 157 CYS A 159 ASP A 168	30B A 500		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["3KEE_A_30BA500","3kee","30B","Simeprevir (DB06290)","Hepatitis c virus;synthetic construct","GENOME POLYPROTEIN","Peptidase_S29",23,"GLN A 41;SER A 42;PHE A 43;VAL A 55;TYR A 56;HIS A 57;GLY A 58;VAL A 78;ASP A 79;GLN A 80;ASP A 81;VAL A 132;LEU A 135;LYS A 136;GLY A 137;SER A 138;SER A 139;PHE A 154;ARG A 155;ALA A 156;ALA A 157;CYS A 159;ASP A 168","30B A 500\r"]]