Results: Ligand

Ligand ID: O31

Drugbank ID:
Glecaprevir
(DB13879)

Indication:
Glecaprevir is a Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C.

LIST OF BINDING INTERFACES for query 'DB13879'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
6P6L_A_O31A1208	6p6l	O31	Glecaprevir (DB13879)	Hepatitis c virus genotype 1a (isolate 1)	NON-STRUCTURAL PROTEIN 4A,SERINE PROTEASE NS3	Peptidase_S29	23	GLN A1041 THR A1042 PHE A1043 VAL A1055 TYR A1056 HIS A1057 GLY A1058 VAL A1078 ASP A1081 ARG A1123 ILE A1132 LEU A1135 LYS A1136 GLY A1137 SER A1138 SER A1139 PHE A1154 ARG A1155 ALA A1156 ALA A1157 VAL A1158 SER A1159 ASP A1168	O31 A1208
6P6S_A_O31A1201	6p6s	O31	Glecaprevir (DB13879)	Hepatitis c virus genotype 3a (isolate nzl1)	NON-STRUCTURAL PROTEIN 4A,SERINE PROTEASE NS3	Peptidase_S29	22	GLN A1041 THR A1042 PHE A1043 VAL A1055 TYR A1056 HIS A1057 GLY A1058 VAL A1078 ASP A1081 LEU A1132 LEU A1135 LYS A1136 GLY A1137 SER A1138 SER A1139 PHE A1154 ARG A1155 ALA A1156 ALA A1157 VAL A1158 SER A1159 GLN A1168	O31 A1201
6P6V_A_O31A1204	6p6v	O31	Glecaprevir (DB13879)	Hepatitis c virus genotype 5a (isolate sa13)	NON-STRUCTURAL PROTEIN 4A,SERINE PROTEASE NS3	Peptidase_S29	23	GLN A1041 THR A1042 PHE A1043 VAL A1055 PHE A1056 HIS A1057 GLY A1058 VAL A1078 ASP A1081 ARG A1123 ILE A1132 LEU A1135 LYS A1136 GLY A1137 SER A1138 SER A1139 PHE A1154 ARG A1155 ALA A1156 ALA A1157 VAL A1158 CYS A1159 ASP A1168	O31 A1204
6P6Z_A_O31A1202	6p6z	O31	Glecaprevir (DB13879)	Hepatitis c virus genotype 4a (isolate ed43)	NON-STRUCTURAL PROTEIN 4A,SERINE PROTEASE NS3	Peptidase_S29	24	GLN A1041 SER A1042 PHE A1043 VAL A1055 TYR A1056 HIS A1057 GLY A1058 VAL A1078 ASP A1079 ASP A1081 ARG A1123 ILE A1132 LEU A1135 LYS A1136 GLY A1137 SER A1138 SER A1139 PHE A1154 ARG A1155 ALA A1156 ALA A1157 VAL A1158 CYS A1159 ASP A1168	O31 A1202
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["6P6L_A_O31A1208","6p6l","O31","Glecaprevir (DB13879)","Hepatitis c virus genotype 1a (isolate 1)","NON-STRUCTURAL PROTEIN 4A,SERINE PROTEASE NS3","Peptidase_S29",23,"GLN A1041;THR A1042;PHE A1043;VAL A1055;TYR A1056;HIS A1057;GLY A1058;VAL A1078;ASP A1081;ARG A1123;ILE A1132;LEU A1135;LYS A1136;GLY A1137;SER A1138;SER A1139;PHE A1154;ARG A1155;ALA A1156;ALA A1157;VAL A1158;SER A1159;ASP A1168","O31 A1208\r"],["6P6S_A_O31A1201","6p6s","O31","Glecaprevir (DB13879)","Hepatitis c virus genotype 3a (isolate nzl1)","NON-STRUCTURAL PROTEIN 4A,SERINE PROTEASE NS3","Peptidase_S29",22,"GLN A1041;THR A1042;PHE A1043;VAL A1055;TYR A1056;HIS A1057;GLY A1058;VAL A1078;ASP A1081;LEU A1132;LEU A1135;LYS A1136;GLY A1137;SER A1138;SER A1139;PHE A1154;ARG A1155;ALA A1156;ALA A1157;VAL A1158;SER A1159;GLN A1168","O31 A1201\r"],["6P6V_A_O31A1204","6p6v","O31","Glecaprevir (DB13879)","Hepatitis c virus genotype 5a (isolate sa13)","NON-STRUCTURAL PROTEIN 4A,SERINE PROTEASE NS3","Peptidase_S29",23,"GLN A1041;THR A1042;PHE A1043;VAL A1055;PHE A1056;HIS A1057;GLY A1058;VAL A1078;ASP A1081;ARG A1123;ILE A1132;LEU A1135;LYS A1136;GLY A1137;SER A1138;SER A1139;PHE A1154;ARG A1155;ALA A1156;ALA A1157;VAL A1158;CYS A1159;ASP A1168","O31 A1204\r"],["6P6Z_A_O31A1202","6p6z","O31","Glecaprevir (DB13879)","Hepatitis c virus genotype 4a (isolate ed43)","NON-STRUCTURAL PROTEIN 4A,SERINE PROTEASE NS3","Peptidase_S29",24,"GLN A1041;SER A1042;PHE A1043;VAL A1055;TYR A1056;HIS A1057;GLY A1058;VAL A1078;ASP A1079;ASP A1081;ARG A1123;ILE A1132;LEU A1135;LYS A1136;GLY A1137;SER A1138;SER A1139;PHE A1154;ARG A1155;ALA A1156;ALA A1157;VAL A1158;CYS A1159;ASP A1168","O31 A1202\r"]]