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| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
|---|---|---|---|---|---|---|---|
| 5hlb | AZR | Aztreonam (DB00355) | Aztreonam is a beta-lactam antibiotic used to treat select aztreonam sensitive gram negative bacteria. | PENICILLIN-BINDING PROTEIN 1B (Escherichia coli (strain k12)) | TransglyTranspeptidaseUB2H | ||
| 5jmn | FUA | Fusidic acid (DB02703) | Fusidic acid is a topical antibacterial agent used to prevent and treat mild to moderate skin infections caused by susceptible bacteria. | MULTIDRUG EFFLUX PUMP SUBUNIT ACRB (Escherichia coli (strain k12);synthetic construct) | ACR_tran | ||
| 6b89 | NOV | Novobiocin (DB01051) | Novobiocin is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds,... | LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB (Escherichia coli (strain k12)) | ABC_tranBCA_ABC_TP_C | ||
| 6h7j | 5FW | Isoprenaline (DB01064) | Isoprenaline is a catecholamine non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block. | BETA-1 ADRENERGIC RECEPTOR (Escherichia coli (strain k12);meleagris gallopavo;lama glama) | 7tm_1 | ||
| 6h7l | Y00 | Dobutamine (DB00841) | Dobutamine is a beta-1 agonist used to treat cardiac decompensation in patients with organic heart disease or from cardiac surgery. | BETA-1 ADRENERGIC RECEPTOR (Escherichia coli (strain k12);meleagris gallopavo;lama glama) | 7tm_1 | ||
| 6h7m | 68H | Levosalbutamol (DB13139) | Levosalbutamol is a beta-2 adrenergic receptor agonist used to treat COPD and asthma. | BETA-1 ADRENERGIC RECEPTOR (Escherichia coli (strain k12);meleagris gallopavo;lama glama) | 7tm_1 | ||
| 6h7n | FVK | Xamoterol (DB13781) | Xamoterol is a β1-adrenoceptor partial agonist that has shown to improve systolic and diastolic function in studies with heart failure patients. It modulates the sympathetic control of the heart but... | BETA-1 ADRENERGIC RECEPTOR (Escherichia coli (strain k12);meleagris gallopavo;lama glama) | 7tm_1 | ||
| 6ibl | H98 | Arformoterol (DB01274) | Arformoterol is a beta-2 adrenergic agonist and bronchodilator used for long term, symptomatic treatment of reversible bronchoconstriction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. | THIOREDOXIN 1,BETA-1 ADRENERGIC RECEPTOR (Escherichia coli (strain k12);meleagris gallopavo;lama glama) | 7tm_1Thioredoxin | ||
| 6rum | TOP | Trimethoprim (DB00440) | Trimethoprim is an antifolate antibiotic often used in combination with sulfamethoxazole to treat a number of infections, including those of the urinary tract, respiratory tract, and gastrointestinal tract. | GFP-LAMA-G97 A GFP ENHANCER NANOBODY WITH CPDHFR INSERTION (Lama glama;escherichia coli (strain k12)) | NA | ||
| 6xg5 | TOP | Trimethoprim (DB00440) | Trimethoprim is an antifolate antibiotic often used in combination with sulfamethoxazole to treat a number of infections, including those of the urinary tract, respiratory tract, and gastrointestinal tract. | DIHYDROFOLATE REDUCTASE (Escherichia coli (strain k12)) | DHFR_1 | ||
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |