(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
|---|---|---|---|---|---|---|---|
| 2rbr | 268 | Phenoxyethanol (DB11304) | Phenoxyethanol is an antiseptic used as a hand disinfectant or preservative in medications. | LYSOZYME (Enterobacteria phage t4) | Phage_lysozyme | ||
| 3ht9 | JZ3 | Guaiacol (DB11359) | Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin.... | LYSOZYME (Enterobacteria phage t4) | Phage_lysozyme | ||
| 3run | CCS | Carbocisteine (DB04339) | Carbocisteine is a expectorant mucolytic used in the relief of respiratory of COPD and other conditions associated with increased mucus viscosity. | LYSOZYME (Enterobacteria phage t4;streptomyces orientalis) | Phage_lysozyme | ||
| 3vw7 | VPX | Vorapaxar (DB09030) | Vorapaxar is a platelet aggregation inhibitor used to reduce thrombotic cardiovascular events in patients with a history of myocardial infarction (MI) or peripheral arterial disease (PAD). | PROTEINASE-ACTIVATED RECEPTOR 1, LYSOZYME (Homo sapiens;enterobacteria phage t4) | 7tm_1Phage_lysozyme | ||
| 4daj | 0HK | Tiotropium (DB01409) | Tiotropium is a long-acting bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). | MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME (Rattus norvegicus;enterobacteria phage t4) | 7tm_1Phage_lysozyme | ||
| 4ldo | ALE | Epinephrine (DB00668) | Epinephrine is a hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma. | LYSOZYME, BETA-2 ADRENERGIC RECEPTOR (Enterobacteria phage t4;homo sapiens;lama glama) | 7tm_1Phage_lysozyme | ||
| 4u15 | 0HK | Tiotropium (DB01409) | Tiotropium is a long-acting bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). | MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARINIC ACETYLCHOLINE RECEPTOR M3 (Rattus norvegicus;enterobacteria phage t4) | 7tm_1 | ||
| 4u16 | 3C0 | Methscopolamine (DB11315) | Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The... | MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARINIC ACETYLCHOLINE RECEPTOR M3 (Rattus norvegicus;enterobacteria phage t4) | 7tm_1 | ||
| 5cxv | 0HK | Tiotropium (DB01409) | Tiotropium is a long-acting bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). | MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARINIC ACETYLCHOLINE RECEPTOR M1 (Homo sapiens;enterobacteria phage t4;synthetic construct) | 7tm_1Phage_lysozyme | ||
| 5dsg | 0HK | Tiotropium (DB01409) | Tiotropium is a long-acting bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). | MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYSIN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Homo sapiens;enterobacteria phage t4) | 7tm_1 | ||
| 5xpr | K86 | Bosentan (DB00559) | Bosentan is a dual endothelin receptor antagonist used to treat pulmonary arterial hypertension. | ENDOTHELIN B RECEPTOR,ENDOLYSIN,ENDOTHELIN B RECEPTOR (Homo sapiens;enterobacteria phage t4) | 7tm_1 | ||
| 6aji | AY6 | Rimonabant (DB06155) | Rimonabant is an anorectic anti-obesity drug produced and marketed by Sanofi-Aventis. It is an inverse agonist for the cannabinoid receptor CB1. Its main avenue of effect is reduction in appetite.... | DRUG EXPORTERS OF THE RND SUPERFAMILY-LIKE PROTEIN,ENDOLYSIN (Mycobacterium smegmatis (strain atcc 700084 / mc(2)155);enterobacteria phage t4) | MMPLPhage_lysozyme | ||
| 6cm4 | 8NU | Risperidone (DB00734) | Risperidone is a second-generation antipsychotic medication used to treat a number of mental health disorders including schizophrenia, bipolar mania, psychosis, or as an adjunct in severe depression. | D(2) DOPAMINE RECEPTOR, ENDOLYSIN CHIMERA (Homo sapiens;enterobacteria phage t4) | 7tm_1Phage_lysozyme | ||
| 6j20 | GBQ | Aprepitant (DB00673) | Aprepitant is a substance P/neurokinin 1 receptor antagonist used to treat nausea and vomiting caused by chemotherapy and surgery. | SUBSTANCE-P RECEPTOR,ENDOLYSIN (Homo sapiens;enterobacteria phage t4) | 7tm_1 | ||
| 6luq | GMJ | Haloperidol (DB00502) | Haloperidol is an antipsychotic agent used to treat schizophrenia and other psychoses, as well as symptoms of agitation, irritability, and delirium. | CHIMERA OF D(2) DOPAMINE RECEPTOR AND ENDOLYSIN (Homo sapiens;enterobacteria phage t4) | 7tm_1Phage_lysozyme | ||
| 6mxt | K5Y | Salmeterol (DB00938) | Salmeterol is a long-acting beta-2 adrenergic receptor agonist used to treat asthma and COPD. | ENDOLYSIN, BETA-2 ADRENERGIC RECEPTOR CHIMERA (Enterobacteria phage t4;homo sapiens;lama glama) | 7tm_1Phage_lysozyme | ||
| 6ol9 | 0HK | Tiotropium (DB01409) | Tiotropium is a long-acting bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). | MUSCARINIC ACETYLCHOLINE RECEPTOR M5, T4 LYSOZYME FUSION (Homo sapiens;enterobacteria phage t4) | 7tm_1Phage_lysozyme | ||
| 6ps3 | CVD | Carvedilol (DB01136) | Carvedilol is a non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients. | FUSION PROTEIN OF BETA-2 ADRENERGIC RECEPTOR AND T4 LYSOZYME (Homo sapiens;enterobacteria phage t4) | 7tm_1Phage_lysozyme | ||
| 6ps6 | TIM | Timolol (DB00373) | Timolol is a non-selective beta adrenergic blocker used in the treatment of elevated intraocular pressure in ocular hypertension or open angle glaucoma. | FUSION PROTEIN OF BETA-2 ADRENERGIC RECEPTOR AND T4 LYSOZYME (Homo sapiens;enterobacteria phage t4) | 7tm_1Phage_lysozyme | ||
| 6vms | 08Y | Bromocriptine (DB01200) | Bromocriptine is a dopamine D2 receptor agonist used for the treatment of galactorrhea due to hyperprolactinemia and other prolactin-related conditions, as well as in early Parkinsonian Syndrome. | ENDOLYSIN,D(2) DOPAMINE RECEPTOR,D(2) DOPAMINE RECEPTOR (Rattus norvegicus;homo sapiens;enterobacteria phage t4) | 7tm_1Phage_lysozyme | ||
| 6wjc | OIN | Atropine (DB00572) | Atropine is a muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs. | MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN FUSION (Homo sapiens;enterobacteria phage t4;dendroaspis angusticeps) | 7tm_1Phage_lysozyme | ||
| 7bts | ALE | Epinephrine (DB00668) | Epinephrine is a hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma. | LYSOZYME-BETA-1 ADRENERGIC RECEPTOR CHIMERA (Enterobacteria phage t4;homo sapiens;vicugna pacos) | Phage_lysozyme | ||
| 7bu6 | E5E | Norepinephrine (DB00368) | Norepinephrine is a sympathomimetic used in the control of blood pressure during various hypotensive states and as an adjunct treatment during cardiac arrest. | ENDOLYSIN,ENDOLYSIN,ENDOLYSIN,BETA-1 ADRENERGIC RECEPTOR CHIMERA (Enterobacteria phage t4;homo sapiens;camelidae mixed library) | Phage_lysozyme | ||
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |