Results: Ligand

Ligand ID: CCS

Drugbank ID:
Carbocisteine
(DB04339)

Indication:
Carbocisteine is a expectorant mucolytic used in the relief of respiratory of COPD and other conditions associated with increased mucus viscosity.

LIST OF BINDING INTERFACES for query 'CCS'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1DSS_G_CCSG149	1dss	CCS	Carbocisteine (DB04339)	Palinurus versicolor	D-GLYCERALDEHYDE-3-PHOSPHATE-DEHYDROGENASE	Gp_dh_C Gp_dh_N	9	SER G 148 THR G 150 THR G 151 ASN G 152 CYS G 153 HIS G 176 TYR G 311 ASN G 313 TYR G 317	CCS G 149
1GTI_A_CCSA47	1gti	CCS	Carbocisteine (DB04339)	Mus musculus	GLUTATHIONE S-TRANSFERASE	GST_C_3 GST_N	12	TRP A 38 LEU A 43 LYS A 44 PRO A 45 THR A 46 LEU A 48 TYR A 49 GLY A 50 GLN A 51 LEU A 52 LYS A 54 TYR A 63	CCS A 47
1L2I_A_CCSA417	1l2i	CCS	Carbocisteine (DB04339)	Homo sapiens; synthetic construct	ESTROGEN RECEPTOR	Hormone_recep	10	PHE A 337 SER A 338 GLU A 339 MET A 342 ASN A 413 GLN A 414 GLY A 415 LYS A 416 VAL A 418 GLU A 419	CCS A 417
1STF_E_CCSE25	1stf	CCS	Carbocisteine (DB04339)	Carica papaya; homo sapiens	PAPAIN; STEFIN B (CYSTATIN B)	Cystatin Peptidase_C1	15	SER I 8 GLY I 9 GLN E 19 CYS E 22 GLY E 23 SER E 24 TRP E 26 ALA E 27 PHE E 28 SER E 29 VAL I 54 VAL I 55 ASP E 158 HIS E 159 ALA E 160	CCS E 25
2JX4_A_CCSA51	2jx4	CCS	Carbocisteine (DB04339)	NA	VASOPRESSIN V2 RECEPTOR	NA	7	GLY A 1 VAL A 226 PHE A 229 THR A 269 VAL A 270 ARG A 271 THR A 273	CCS A 51
3DMT_C_CCSC166	3dmt	CCS	Carbocisteine (DB04339)	Trypanosoma cruzi	GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, GLYCOSOMAL	Gp_dh_C Gp_dh_N	10	ALA C 164 SER C 165 THR C 167 THR C 168 ASN C 169 CYS C 170 HIS C 194 TYR C 333 ASN C 335 TYR C 339	CCS C 166
3PQZ_L_CCSL11	3pqz	CCS	Carbocisteine (DB04339)	Homo sapiens; synthetic construct	CYCLIC PEPTIDE; GROWTH FACTOR RECEPTOR-BOUND PROTEIN 7	SH2	9	TRP L 1 ASN L 7 THR L 8 PHE L 9 PRO L 10 HIS D 479 TYR D 480 LEU D 481 MET D 495	CCS L 11
3RUL_A_CCSA76	3rul	CCS	Carbocisteine (DB04339)	Homo sapiens; synthetic construct	UBIQUITIN	ubiquitin	3	ARG A 74 GLY A 75 LYS A 77	CCS A 76
3RUM_A_CCSA375	3rum	CCS	Carbocisteine (DB04339)	Escherichia coli k-12; amycolatopsis lurida	MALTOSE-BINDING PERIPLASMIC PROTEIN	SBP_bac_1	4	GLN A 73 SER A 74 GLY A 374 LYS A 376	CCS A 375
3RUN_A_CCSA165	3run	CCS	Carbocisteine (DB04339)	Enterobacteria phage t4; streptomyces orientalis	LYSOZYME	Phage_lysozyme	3	ASN A 163 ALA A 164 LYS A 166	CCS A 165
4EYZ_A_CCSA109	4eyz	CCS	Carbocisteine (DB04339)	Ruminococcus flavefaciens	CELLULOSOME-RELATED PROTEIN MODULE FROM RUMINOCOCCUS FLAVEFACIENS THAT RESEMBLES PAPAIN-LIKE CYSTEINE PEPTIDASES	NA	14	TYR A 71 ASN A 108 GLY A 111 PHE A 112 VAL A 113 ASN A 213 HIS A 214 HIS A 215 ILE A 216 SER A 231 GLY A 232 PRO A 233 LEU A 240 ALA A 253	CCS A 109
4W9N_C_CCSC1548	4w9n	CCS	Carbocisteine (DB04339)	Homo sapiens	ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE	ADH_zinc_N	5	HIS C1530 ALA C1531 PHE C1532 TRP C1546 VAL C1547	CCS C1548
5O45_B_CCSB13	5o45	CCS	Carbocisteine (DB04339)	Homo sapiens; synthetic construct	PHE-MEA-9KK-SAR-ASP-VAL-MEA-TYR-SAR-TRP-TYR-LEU-CCS-GLY-NH2; PROGRAMMED CELL DEATH 1 LIGAND 1	V-set	11	PHE B 1 TYR B 11 LEU B 12 GLY B 14 TYR A 56 GLU A 58 ASP A 61 LYS A 62 ASN A 63 GLN A 66 VAL A 76	CCS B 13
5O4Y_A_CCSA14	5o4y	CCS	Carbocisteine (DB04339)	Homo sapiens; synthetic construct	PHE-MAA-ASN-PRO-HIS-LEU-SER-TRP-SER-TRP-9KK-9KK-ARG-CCS-GLY-NH2	NA	8	PHE A 1 ASN A 3 LEU A 6 SER A 7 TRP A 8 SER A 9 ARG A 13 GLY A 15	CCS A 14
6E5Z_A_CCSA106	6e5z	CCS	Carbocisteine (DB04339)	Homo sapiens	PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1	DJ-1_PfpI	16	GLU A 15 GLU A 18 GLY A 74 GLY A 75 ASN A 76 ILE A 105 ALA A 107 GLY A 108 PRO A 109 THR A 125 HIS A 126 ALA A 129 SER A 155 ARG A 156 GLY A 157 PRO A 158	CCS A 106
6YCR_B_CCSB12	6ycr	CCS	Carbocisteine (DB04339)	Homo sapiens; synthetic construct	FFIVIRDRVFR(CCS)G(NH2); PROGRAMMED CELL DEATH 1 LIGAND 1	V-set	8	PHE B 1 PHE B 2 PHE B 10 ARG B 11 GLY B 13 TYR A 56 GLN A 66 VAL A 76	CCS B 12
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1DSS_G_CCSG149","1dss","CCS","Carbocisteine (DB04339)","Palinurus versicolor","D-GLYCERALDEHYDE-3-PHOSPHATE-DEHYDROGENASE","Gp_dh_C;Gp_dh_N",9,"SER G 148;THR G 150;THR G 151;ASN G 152;CYS G 153;HIS G 176;TYR G 311;ASN G 313;TYR G 317","CCS G 149\r"],["1GTI_A_CCSA47","1gti","CCS","Carbocisteine (DB04339)","Mus musculus","GLUTATHIONE S-TRANSFERASE","GST_C_3;GST_N",12,"TRP A  38;LEU A  43;LYS A  44;PRO A  45;THR A  46;LEU A  48;TYR A  49;GLY A  50;GLN A  51;LEU A  52;LYS A  54;TYR A  63","CCS A  47\r"],["1L2I_A_CCSA417","1l2i","CCS","Carbocisteine (DB04339)","Homo sapiens;synthetic construct","ESTROGEN RECEPTOR","Hormone_recep",10,"PHE A 337;SER A 338;GLU A 339;MET A 342;ASN A 413;GLN A 414;GLY A 415;LYS A 416;VAL A 418;GLU A 419","CCS A 417\r"],["1STF_E_CCSE25","1stf","CCS","Carbocisteine (DB04339)","Carica papaya;homo sapiens","PAPAIN;STEFIN B (CYSTATIN B)","Cystatin;Peptidase_C1",15,"SER I   8;GLY I   9;GLN E  19;CYS E  22;GLY E  23;SER E  24;TRP E  26;ALA E  27;PHE E  28;SER E  29;VAL I  54;VAL I  55;ASP E 158;HIS E 159;ALA E 160","CCS E  25\r"],["2JX4_A_CCSA51","2jx4","CCS","Carbocisteine (DB04339)","NA","VASOPRESSIN V2 RECEPTOR","NA",7,"GLY A   1;VAL A 226;PHE A 229;THR A 269;VAL A 270;ARG A 271;THR A 273","CCS A  51\r"],["3DMT_C_CCSC166","3dmt","CCS","Carbocisteine (DB04339)","Trypanosoma cruzi","GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, GLYCOSOMAL","Gp_dh_C;Gp_dh_N",10,"ALA C 164;SER C 165;THR C 167;THR C 168;ASN C 169;CYS C 170;HIS C 194;TYR C 333;ASN C 335;TYR C 339","CCS C 166\r"],["3PQZ_L_CCSL11","3pqz","CCS","Carbocisteine (DB04339)","Homo sapiens;synthetic construct","CYCLIC PEPTIDE;GROWTH FACTOR RECEPTOR-BOUND PROTEIN 7","SH2",9,"TRP L   1;ASN L   7;THR L   8;PHE L   9;PRO L  10;HIS D 479;TYR D 480;LEU D 481;MET D 495","CCS L  11\r"],["3RUL_A_CCSA76","3rul","CCS","Carbocisteine (DB04339)","Homo sapiens;synthetic construct","UBIQUITIN","ubiquitin",3,"ARG A  74;GLY A  75;LYS A  77","CCS A  76\r"],["3RUM_A_CCSA375","3rum","CCS","Carbocisteine (DB04339)","Escherichia coli k-12;amycolatopsis lurida","MALTOSE-BINDING PERIPLASMIC PROTEIN","SBP_bac_1",4,"GLN A  73;SER A  74;GLY A 374;LYS A 376","CCS A 375\r"],["3RUN_A_CCSA165","3run","CCS","Carbocisteine (DB04339)","Enterobacteria phage t4;streptomyces orientalis","LYSOZYME","Phage_lysozyme",3,"ASN A 163;ALA A 164;LYS A 166","CCS A 165\r"],["4EYZ_A_CCSA109","4eyz","CCS","Carbocisteine (DB04339)","Ruminococcus flavefaciens","CELLULOSOME-RELATED PROTEIN MODULE FROM RUMINOCOCCUS FLAVEFACIENS THAT RESEMBLES PAPAIN-LIKE CYSTEINE PEPTIDASES","NA",14,"TYR A  71;ASN A 108;GLY A 111;PHE A 112;VAL A 113;ASN A 213;HIS A 214;HIS A 215;ILE A 216;SER A 231;GLY A 232;PRO A 233;LEU A 240;ALA A 253","CCS A 109\r"],["4W9N_C_CCSC1548","4w9n","CCS","Carbocisteine (DB04339)","Homo sapiens","ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE","ADH_zinc_N",5,"HIS C1530;ALA C1531;PHE C1532;TRP C1546;VAL C1547","CCS C1548\r"],["5O45_B_CCSB13","5o45","CCS","Carbocisteine (DB04339)","Homo sapiens;synthetic construct","PHE-MEA-9KK-SAR-ASP-VAL-MEA-TYR-SAR-TRP-TYR-LEU-CCS-GLY-NH2;PROGRAMMED CELL DEATH 1 LIGAND 1","V-set",11,"PHE B   1;TYR B  11;LEU B  12;GLY B  14;TYR A  56;GLU A  58;ASP A  61;LYS A  62;ASN A  63;GLN A  66;VAL A  76","CCS B  13\r"],["5O4Y_A_CCSA14","5o4y","CCS","Carbocisteine (DB04339)","Homo sapiens;synthetic construct","PHE-MAA-ASN-PRO-HIS-LEU-SER-TRP-SER-TRP-9KK-9KK-ARG-CCS-GLY-NH2","NA",8,"PHE A   1;ASN A   3;LEU A   6;SER A   7;TRP A   8;SER A   9;ARG A  13;GLY A  15","CCS A  14\r"],["6E5Z_A_CCSA106","6e5z","CCS","Carbocisteine (DB04339)","Homo sapiens","PROTEIN\/NUCLEIC ACID DEGLYCASE DJ-1","DJ-1_PfpI",16,"GLU A  15;GLU A  18;GLY A  74;GLY A  75;ASN A  76;ILE A 105;ALA A 107;GLY A 108;PRO A 109;THR A 125;HIS A 126;ALA A 129;SER A 155;ARG A 156;GLY A 157;PRO A 158","CCS A 106\r"],["6YCR_B_CCSB12","6ycr","CCS","Carbocisteine (DB04339)","Homo sapiens;synthetic construct","FFIVIRDRVFR(CCS)G(NH2);PROGRAMMED CELL DEATH 1 LIGAND 1","V-set",8,"PHE B   1;PHE B   2;PHE B  10;ARG B  11;GLY B  13;TYR A  56;GLN A  66;VAL A  76","CCS B  12\r"]]