Ligand ID: CVD

Drugbank ID:
Carvedilol
(DB01136)

Indication:
Carvedilol is a non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients.

LIST OF BINDING INTERFACES for query 'DB01136'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
4AMJ_A_CVDA1359	4amj	CVD	Carvedilol (DB01136)	Meleagris gallopavo	BETA-1 ADRENERGIC RECEPTOR	7tm_1	22	GLY A  98 VAL A 102 TRP A 117 ASP A 121 VAL A 122 VAL A 125 THR A 126 PHE A 201 THR A 203 TYR A 207 ALA A 208 SER A 211 SER A 212 SER A 215 TRP A 303 PHE A 306 PHE A 307 ASN A 310 VAL A 326 ASN A 329 TRP A 330 TYR A 333	CVD A1359		Details
6PS3_A_CVDA1201	6ps3	CVD	Carvedilol (DB01136)	Homo sapiens; enterobacteria phage t4	FUSION PROTEIN OF BETA-2 ADRENERGIC RECEPTOR AND T4 LYSOZYME	7tm_1 Phage_lysozyme	25	GLY A  90 HIS A  93 ILE A  94 TRP A 109 ASP A 113 VAL A 114 VAL A 117 THR A 118 CYS A 191 PHE A 193 THR A 195 TYR A 199 ALA A 200 SER A 203 SER A 204 SER A 207 TRP A 286 PHE A 289 PHE A 290 ASN A 293 TYR A 308 ILE A 309 ASN A 312 TRP A 313 TYR A 316	CVD A1201		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["4AMJ_A_CVDA1359","4amj","CVD","Carvedilol (DB01136)","Meleagris gallopavo","BETA-1 ADRENERGIC RECEPTOR","7tm_1",22,"GLY A 98;VAL A 102;TRP A 117;ASP A 121;VAL A 122;VAL A 125;THR A 126;PHE A 201;THR A 203;TYR A 207;ALA A 208;SER A 211;SER A 212;SER A 215;TRP A 303;PHE A 306;PHE A 307;ASN A 310;VAL A 326;ASN A 329;TRP A 330;TYR A 333","CVD A1359\r"],["6PS3_A_CVDA1201","6ps3","CVD","Carvedilol (DB01136)","Homo sapiens;enterobacteria phage t4","FUSION PROTEIN OF BETA-2 ADRENERGIC RECEPTOR AND T4 LYSOZYME","7tm_1;Phage_lysozyme",25,"GLY A 90;HIS A 93;ILE A 94;TRP A 109;ASP A 113;VAL A 114;VAL A 117;THR A 118;CYS A 191;PHE A 193;THR A 195;TYR A 199;ALA A 200;SER A 203;SER A 204;SER A 207;TRP A 286;PHE A 289;PHE A 290;ASN A 293;TYR A 308;ILE A 309;ASN A 312;TRP A 313;TYR A 316","CVD A1201\r"]]