Ligand ID: CED


Drugbank ID:
DB04133
(Degraded Cephaloridine)


Indication:

Get human targets for CED in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'CED' AND SARS-RELATED PROTEINS ONLY

1) User may click on the DrReposER ID (the first column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera throuh AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		1q2w 3C-LIKE PROTEASE
(SARSr-CoV)		5 / 12
ALA B 116
TYR B 118
ASN B  28
GLY B 124
ARG A 298
1.74A20.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		1qz8 POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
ALA B  54
TYR B  87
THR B  18
GLY B  17
ALA B  16
1.62A19.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		1qz8 POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
ALA A  16
HIS A  48
ASN A  27
ALA A  15
ARG A  55
1.71A19.70
None
SO4  A 693 (-4.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		1uj1 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER B 144
TYR B 161
SER B 147
ILE B 136
GLY B 143
1.74A20.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		1uk2 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
SER B 144
SER B 147
ASN B  28
ASN B 119
GLY B 143
1.57A24.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		1uk2 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
SER B 144
SER B 147
ASN B  28
ASN B 119
GLY B 143
1.59A24.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		1uk2 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A 123
ASN A 142
GLY A 124
ALA A 116
TYR A 126
1.42A23.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		1uk2 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A 123
ASN A  28
GLY A 124
ALA A 116
TYR A 126
1.41A24.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		1uk2 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A 123
ASN A 142
GLY A 124
ALA A 116
TYR A 126
1.39A23.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		1uk2 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER B 144
SER B 147
ASN B  28
ASN B 119
GLY B 143
1.58A23.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		1uw7 NSP9
(SARS-COV
HKU-39849)		5 / 12
ALA A  16
HIS A  48
ASN A  27
ALA A  15
ARG A  55
1.70A20.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		5 / 11
ALA B 232
TYR B 250
SER B 247
ASN B 219
ALA B 221
1.74A21.05
GOL  B1004 (-3.5A)
None
None
None
GOL  B1004 (-4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		5 / 12
ALA B 294
ASN B 299
SER B 262
GLY B 260
ALA B 293
1.63A20.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		5 / 12
ALA B 294
ASN B 299
SER B 262
GLY B 260
ALA B 293
1.63A22.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		5 / 12
ALA B 294
ASN B 299
SER B 262
GLY B 260
ALA B 293
1.64A22.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		5 / 12
ALA B 294
ASN B 299
SER B 262
GLY B 260
ALA B 293
1.64A20.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
(SARSr-CoV)		5 / 12
SER F 156
ASN F 114
ASN F 110
ALA F 157
ARG F 195
1.52A22.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
(SARSr-CoV)		5 / 12
SER F 156
ASN F 114
ASN F 110
ALA F 157
ARG F 195
1.52A22.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		2ajf ACE2
(Homo
sapiens)		5 / 12
ALA B  46
SER B  47
ASN B  51
ILE B  54
SER B  43
1.65A18.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		5 / 12
ALA F 314
SER F 313
TYR E 269
GLY F 317
ARG E 278
1.63A16.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		2dd8 IGG LIGHT CHAIN
(Homo
sapiens)		5 / 12
LYS L 167
ASN L 172
GLU L  83
ALA L  84
TYR L  86
1.50A18.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		5 / 12
ASN C 100
ASN B 100
ASN C  41
GLY C  47
ALA C  51
1.59A22.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		5 / 12
ALA A 113
ASN A 118
SER A  81
GLY A  79
ALA A 112
1.62A21.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		5 / 11
ALA B  51
TYR B  69
SER B  66
ASN B  38
ALA B  40
1.74A21.18
APR  B 477 ( 3.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		5 / 12
ALA A 113
ASN A 118
SER A  81
GLY A  79
ALA A 112
1.61A21.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		5 / 12
ASN C 100
ASN B 100
ASN C  41
GLY C  47
ALA C  51
1.59A22.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
SER C 246
ASN C 263
THR C 211
GLY C 210
ALA C 247
1.75A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
SER C 246
ASN C 263
THR C 211
GLY C 210
ALA C 247
1.73A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
SER B 246
ASN B 263
THR B 211
GLY B 210
ALA B 247
1.67A22.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		2ghw ANTI-SCFV ANTIBODY,
80R
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		5 / 12
ALA B  33
SER B  52
ASN B  74
SER B  56
ARG A 426
1.61A21.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		2ghw ANTI-SCFV ANTIBODY,
80R
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		5 / 12
ALA B  33
SER B  52
ASN B  74
SER B  56
ARG A 426
1.58A21.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		2qc2 3C-LIKE PROTEINASE
(-)		5 / 12
SER A 123
ASN A 142
GLY A 124
ALA A 116
TYR A 126
1.38A23.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		2qc2 3C-LIKE PROTEINASE
(-)		5 / 12
SER A 123
ASN A 142
GLY A 124
ALA A 116
TYR A 126
1.44A23.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		5 / 12
SER A 123
ASN A 142
GLY A 124
ALA A 116
TYR A 126
1.71A23.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		5 / 12
SER A 123
ASN A 142
GLY A 124
ALA A 116
TYR A 126
1.69A23.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		2xyq PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
SER A  74
TYR A  47
ASN A  43
GLY A  73
ALA A  72
1.72A22.42
SAH  A1293 (-4.1A)
SAH  A1293 (-4.8A)
SAH  A1293 (-3.8A)
SAH  A1293 (-4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		2xyq NSP10
PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
ALA A  79
SER A  74
ASN A  43
GLY A  77
ARG B  78
1.79A23.16
None
SAH  A1293 (-4.1A)
SAH  A1293 (-3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		2xyr NSP10
PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
ALA A  79
SER A  74
ASN A  43
GLY A  77
ARG B  78
1.78A21.24
None
SFG  A1298 ( 4.2A)
SFG  A1298 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		2xyr PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
SER A  74
TYR A  47
ASN A  43
GLY A  73
ALA A  72
1.70A22.29
SFG  A1298 ( 4.2A)
SFG  A1298 (-4.6A)
SFG  A1298 (-3.5A)
SFG  A1298 (-4.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		3d0h ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
ALA B  65
ASN B  58
TYR B  50
SER B  47
GLY B  66
1.48A18.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		3d0h ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
ALA B  65
ASN B  58
TYR B  50
SER B  47
GLY B  66
1.48A18.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		3d0i ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
SER A 105
SER A 113
ASN A 117
SER A 106
GLY A 104
1.63A18.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		3ea7 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER B 123
ASN B 142
GLY B 124
ALA B 116
TYR B 126
1.68A22.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		3ea7 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER B 123
ASN B 142
GLY B 124
ALA B 116
TYR B 126
1.66A23.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		3ee7 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 11
ALA A  16
ASN A  27
THR A  18
GLY A  17
ALA A  22
1.74A18.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		3ee7 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
ALA B  28
SER B  46
HIS B  48
ASN B  27
ALA B  16
1.76A18.66
None
None
PO4  B 122 (-3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ALA B 140
SER B 144
TYR B 161
SER B 147
ILE B 136
1.77A20.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		3f9h 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LYS A   2
SER B 139
ASN A 214
ILE A 213
ARG A 298
1.79A20.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		3f9h 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ALA A 116
SER A 144
ASN A  28
GLY A 143
TYR A 161
1.69A23.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		3fzd 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A 123
ASN A 119
GLY A 124
ALA A 116
TYR A 126
1.54A23.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		3fzd 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A 123
ASN A 119
GLY A 124
ALA A 116
TYR A 126
1.50A24.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		3fzd 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A 123
ASN A 119
GLY A 124
ALA A 116
TYR A 126
1.52A24.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER B 123
ASN B 142
GLY B 124
ALA B 116
TYR B 126
1.43A22.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER B 123
ASN B 142
GLY B 124
ALA B 116
TYR B 126
1.41A22.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		3mj5 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
SER B 246
ASN B 263
THR B 211
GLY B 210
ALA B 247
1.69A22.22
None
None
None
GRM  A 801 (-3.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		3mj5 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
ASN B 129
SER A  79
THR B 201
GLY B 202
ALA B 182
1.66A21.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		3mj5 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
ASN B 129
SER A  79
THR B 201
GLY B 202
ALA B 182
1.69A21.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		3r24 2'-O-METHYL
TRANSFERASE
NSP10 AND NSP11
(SARSr-CoV)		5 / 10
ALA A  79
SER A  74
ASN A  43
GLY A  77
ARG B  78
1.75A24.49
None
SAM  A 302 ( 4.4A)
SAM  A 302 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		3r24 2'-O-METHYL
TRANSFERASE
NSP10 AND NSP11
(SARSr-CoV)		5 / 12
ALA A  79
SER A  74
ASN A  43
GLY A  77
ARG B  78
1.72A23.77
None
SAM  A 302 ( 4.4A)
SAM  A 302 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		3r24 2'-O-METHYL
TRANSFERASE
NSP10 AND NSP11
(SARSr-CoV)		5 / 11
ALA A  79
SER A  74
ASN A  43
GLY A  77
ARG B  78
1.76A24.49
None
SAM  A 302 ( 4.4A)
SAM  A 302 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		3r24 2'-O-METHYL
TRANSFERASE
NSP10 AND NSP11
(SARSr-CoV)		5 / 12
ALA A  79
SER A  74
ASN A  43
GLY A  77
ARG B  78
1.79A23.58
None
SAM  A 302 ( 4.4A)
SAM  A 302 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		3r24 2'-O-METHYL
TRANSFERASE
NSP10 AND NSP11
(SARSr-CoV)		5 / 12
ALA A  79
SER A  74
ASN A  43
GLY A  77
ARG B  78
1.77A23.58
None
SAM  A 302 ( 4.4A)
SAM  A 302 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
SER A  74
TYR A  47
ASN A  43
GLY A  73
ALA A  72
1.75A24.49
SAM  A 302 ( 4.4A)
SAM  A 302 (-4.5A)
SAM  A 302 (-3.5A)
SAM  A 302 (-4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		3r24 2'-O-METHYL
TRANSFERASE
NSP10 AND NSP11
(SARSr-CoV)		5 / 12
ALA A  79
SER A  74
ASN A  43
GLY A  77
ARG B  78
1.77A24.49
None
SAM  A 302 ( 4.4A)
SAM  A 302 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
SER B 105
SER B 113
ASN B 117
SER B 106
GLY B 104
1.54A18.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
ALA A  65
ASN A  58
TYR A  50
SER A  47
GLY A  66
1.64A18.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		3scl ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 10
ALA A  65
TYR A  50
SER A  47
ASN A  61
GLY A  66
1.54A18.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		3scl ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
ALA A  65
ASN A  58
TYR A  50
SER A  47
GLY A  66
1.50A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		4m0w REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
SER A 246
ASN A 263
THR A 211
GLY A 210
ALA A 247
1.67A21.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		4mm3 PAPAIN-LIKE
PROTEINASE
(SARSr-CoV)		5 / 12
SER B 181
ASN B 129
ASN B 178
GLU B 180
ALA B 182
1.75A22.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		4tww 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A 147
ILE A 136
SER A 123
GLY A 124
ARG B 298
1.78A20.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
ALA B 270
SER B 271
ASN B 266
GLY B 110
ALA B 274
1.76A17.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
ALA B 270
SER B 271
ASN B 266
GLY B 110
ALA B 274
1.78A17.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		5c8t GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
ALA B 270
SER B 271
ASN B 266
GLY B 110
ALA B 274
1.78A18.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		5e6j REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 11
ALA D 150
TYR D  36
SER D  86
THR D 159
ALA D 154
1.78A21.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		5f22 NSP8
(SARSr-CoV)		5 / 12
SER B 156
ASN B 114
ASN B 110
ALA B 157
ARG B 195
1.62A20.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		5f22 NSP8
(SARSr-CoV)		5 / 12
SER B 156
ASN B 114
ASN B 110
ALA B 157
ARG B 195
1.61A20.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		5f22 NSP8
(SARSr-CoV)		5 / 12
SER B 156
ASN B 114
ASN B 110
ALA B 157
ARG B 195
1.58A19.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		5f22 NSP8
(SARSr-CoV)		5 / 12
SER B 156
ASN B 114
ASN B 110
ALA B 157
ARG B 195
1.58A19.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 12
ALA D 270
SER D 271
ASN D 266
GLY D 110
ALA D 274
1.78A18.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		5tl7 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
ALA D  40
TYR D  28
ILE D  45
SER D  86
GLY D  39
1.55A22.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		5wrg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ALA B 753
SER B 750
TYR A 300
ILE A 299
SER B 717
1.58A11.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		5x4r S PROTEIN
(MERS-CoV)		5 / 12
ALA A 311
SER A 126
ASN A 125
ALA A 122
ARG A  46
1.33A21.29
None
None
NAG  A 502 (-1.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		5x4r S PROTEIN
(MERS-CoV)		5 / 12
ALA A 311
SER A 126
ASN A 125
ALA A 122
ARG A  46
1.33A21.29
None
None
NAG  A 502 (-1.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		5x4r S PROTEIN
(MERS-CoV)		5 / 11
ALA A 311
SER A 126
ASN A 125
ALA A 122
ARG A  46
1.34A21.01
None
None
NAG  A 502 (-1.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		5x4r S PROTEIN
(MERS-CoV)		5 / 12
ALA A 311
SER A 126
ASN A 125
ALA A 122
ARG A  46
1.33A20.73
None
None
NAG  A 502 (-1.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		5x4r S PROTEIN
(MERS-CoV)		5 / 12
ALA A 311
SER A 126
ASN A 125
ALA A 122
ARG A  46
1.33A21.01
None
None
NAG  A 502 (-1.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		5x4r S PROTEIN
(MERS-CoV)		5 / 12
ALA A 311
SER A 126
ASN A 125
ALA A 122
ARG A  46
1.35A20.73
None
None
NAG  A 502 (-1.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		5x59 S PROTEIN
(MERS-CoV)		5 / 12
LYS A1100
SER A 852
ASN A 848
SER C1114
GLY C1115
1.37A11.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 11
SER B 861
TYR A 689
THR B 863
GLY B 862
ALA B 866
1.44A12.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
SER B 861
TYR A 689
THR B 863
GLY B 862
ALA B 866
1.45A12.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
SER B 861
TYR A 689
THR B 863
GLY B 862
ALA B 866
1.45A12.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
ALA C 753
SER C 750
TYR B 598
ILE B 299
SER C 717
1.51A11.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
ASN C1090
THR A 863
GLY A 867
ALA A 866
TYR A 771
1.77A12.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		5x5c S PROTEIN
(MERS-CoV)		5 / 12
ALA B 311
SER B 126
ASN B 125
ALA B 122
ARG B  46
1.31A11.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		5x5c S PROTEIN
(MERS-CoV)		5 / 12
ALA B 311
SER B 126
ASN B 125
ALA B 122
ARG B  46
1.30A11.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		5x5c S PROTEIN
(MERS-CoV)		5 / 12
ALA B 311
SER B 126
ASN B 125
ALA B 122
ARG B  46
1.30A11.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		5x5c S PROTEIN
(MERS-CoV)		5 / 12
ALA B 311
SER B 126
ASN B 125
ALA B 122
ARG B  46
1.31A11.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		5x5c S PROTEIN
(MERS-CoV)		5 / 12
ALA B 311
SER B 126
ASN B 125
ALA B 122
ARG B  46
1.29A11.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ASN B1116
HIS B1065
GLY B1113
ALA B1062
TYR A 899
1.77A12.22
ASN  B1116 ( 0.6A)
HIS  B1065 ( 1.0A)
GLY  B1113 ( 0.0A)
ALA  B1062 ( 0.0A)
TYR  A 899 ( 1.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ALA C 866
ASN A1056
THR C 869
GLY C 867
ALA C 875
1.70A12.02
ALA  C 866 ( 0.0A)
ASN  A1056 ( 0.6A)
THR  C 869 ( 0.8A)
GLY  C 867 ( 0.0A)
ALA  C 875 ( 0.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ALA C 866
ASN A1056
THR C 869
GLY C 867
ALA C 875
1.72A12.22
ALA  C 866 ( 0.0A)
ASN  A1056 ( 0.6A)
THR  C 869 ( 0.8A)
GLY  C 867 ( 0.0A)
ALA  C 875 ( 0.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ASN A1056
THR C 869
GLY C 867
ALA C 866
TYR C 771
1.22A12.22
ASN  A1056 ( 0.6A)
THR  C 869 ( 0.8A)
GLY  C 867 ( 0.0A)
ALA  C 866 ( 0.0A)
TYR  C 771 ( 1.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		6acc SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
ALA A 858
SER A 861
TYR B 689
THR A 863
GLY A 862
1.73A12.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		6acd SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER A1052
GLU A1054
GLY C 873
ALA C 874
TYR C 771
1.48A12.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6acd SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 11
ALA B 639
TYR B 598
THR B 624
GLY B 638
ALA B 595
1.70A12.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		6acd SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER A 111
ASN A 129
ILE B 455
GLN A 112
GLY A 104
1.65A11.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6acd SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ALA B 639
TYR B 598
THR B 624
GLY B 638
ALA B 595
1.69A12.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER B1093
ASN B 896
GLU C1074
THR B1087
ARG B1073
1.67A12.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ASN A1056
THR C 869
GLY C 867
ALA C 866
TYR C 771
1.51A12.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 10
ALA C 590
SER C 591
SER C 592
THR C 588
GLY C 587
1.74A12.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
SER A 861
TYR C 689
THR A 863
GLY A 862
ALA A 866
1.78A12.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
ALA B 590
SER B 591
SER B 592
THR B 588
GLY B 587
1.71A12.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		6crw SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
ALA B 954
SER B 956
GLN B 974
SER B 957
ARG B 982
1.54A11.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		6crx SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
SER B 680
SER B 645
GLU B 647
GLY B 682
ALA B 683
1.58A12.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6crz SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 11
SER C 861
TYR B 689
THR C 863
GLY C 862
ALA C 866
1.62A12.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		6cs0 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
ALA A 875
TYR A 886
GLY A 871
ALA A 872
TYR C1029
1.48A12.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
ALA B 237
ASN B 135
ASN B  78
THR B 247
GLY B 246
1.55A12.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
ALA B 237
ASN B 135
ASN B  78
THR B 247
GLY B 246
1.57A12.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
ALA B 237
ASN B 135
ASN B  78
THR B 247
GLY B 246
1.57A12.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 10
ALA B 858
SER B 861
TYR A 689
THR B 863
GLY B 862
1.63A12.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		6cs2 ACE2
(Homo
sapiens)		5 / 12
SER D 105
SER D 113
ASN D 117
SER D 106
GLY D 104
1.76A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6jyt HELICASE
(SARSr-CoV)		5 / 12
ALA B 379
ASN B 124
TYR B 120
ASN B 423
ALA B 407
1.73A19.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		6m0j ACE2
(Homo
sapiens)		5 / 12
SER A 105
SER A 113
ASN A 117
SER A 106
GLY A 104
1.73A18.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		6m17 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
ALA C 117
SER C 118
ILE C 496
SER C 100
GLY C 115
1.38A16.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		6m18 ACE2
(Homo
sapiens)		5 / 12
SER D 105
SER D 113
ASN D 117
SER D 106
GLY D 104
1.65A16.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6m1d ACE2
(Homo
sapiens)		5 / 12
ALA B  65
SER B  43
ASN B  49
ASN B  61
GLY B  66
1.71A16.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6m1d ACE2
(Homo
sapiens)		5 / 12
ALA B  65
SER B  43
ASN B  49
ASN B  61
GLY B  66
1.67A16.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER B 861
TYR C 689
THR B 863
GLY B 862
ALA B 866
1.38A11.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 11
SER B 861
TYR C 689
THR B 863
GLY B 862
ALA B 866
1.39A11.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER B 861
TYR C 689
THR B 863
GLY B 862
ALA B 866
1.41A11.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER B1105
TYR A 899
ASN A 896
GLY B1106
ALA B1069
1.78A11.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6nb7 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ALA A 938
ASN A 838
ASN A 942
ALA A 940
ARG A 996
1.65A11.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6nur NSP12
(SARSr-CoV)		5 / 12
TYR A 453
ASN A 543
THR A 540
GLY A 559
ALA A 558
1.37A14.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		6nur NSP8
(SARSr-CoV)		5 / 12
SER D 151
ASN D 109
ASN D 105
ALA D 152
ARG D 190
1.59A22.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6nur NSP12
(SARSr-CoV)		5 / 12
SER A 709
ASN A 703
ASN A 781
ARG A 132
TYR A 788
1.52A14.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		6nur NSP8
(SARSr-CoV)		5 / 12
SER D 151
ASN D 109
ASN D 105
ALA D 152
ARG D 190
1.58A22.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6nur NSP12
(SARSr-CoV)		5 / 11
TYR A 453
ASN A 543
THR A 540
GLY A 559
ALA A 558
1.43A14.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6vw1 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER F 477
THR F 478
GLY F 476
ALA F 475
TYR F 489
1.58A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 12
ALA L  51
SER L  52
ASN L  29
ASN L  31
THR L  53
1.33A22.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
ALA L  57
SER L  58
ASN L  35
THR L  59
TYR L  97
1.74A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
SER C  73
ASN C  35
ASN C  37
GLY C  72
ALA C  57
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
ALA C  57
SER C  58
ASN C  35
THR C  59
TYR C  97
1.76A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6ym0 LIGHT CHAIN
(Homo
sapiens)		5 / 12
SER L  73
ASN L  35
ASN L  37
GLY L  72
ALA L  57
1.61A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6ym0 LIGHT CHAIN
(Homo
sapiens)		5 / 12
ALA L  57
SER L  58
ASN L  35
THR L  59
TYR L  97
1.75A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 12
ALA L  57
SER L  58
ASN L  35
THR L  59
TYR L  97
1.73A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 12
ALA C  57
SER C  58
ASN C  35
THR C  59
TYR C  97
1.73A20.36
None