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| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
|---|---|---|---|---|---|---|---|
| 1dfo | FFO | Levoleucovorin (DB11596) | Levoleucovorin is a folate analog used after high dose methotrexate for osteosarcoma, to reduce the toxic effects of folate analogs, and with 5-fluorouracil in palliative treatment of advanced metastatic colorectal cancer. | SERINE HYDROXYMETHYLTRANSFERASE (Escherichia coli) | SHMT | ||
| 2vmy | FFO | Levoleucovorin (DB11596) | Levoleucovorin is a folate analog used after high dose methotrexate for osteosarcoma, to reduce the toxic effects of folate analogs, and with 5-fluorouracil in palliative treatment of advanced metastatic colorectal cancer. | SERINE HYDROXYMETHYLTRANSFERASE (Bacillus stearothermophilus) | SHMT | ||
| 6qvl | 4DW | Pemetrexed (DB00642) | Pemetrexed is a folate analog used to treat mesothelioma and non-small cell lung cancer. | SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL (Homo sapiens) | SHMT | ||
| 6uxj | FFO | Levoleucovorin (DB11596) | Levoleucovorin is a folate analog used after high dose methotrexate for osteosarcoma, to reduce the toxic effects of folate analogs, and with 5-fluorouracil in palliative treatment of advanced metastatic colorectal cancer. | SERINE HYDROXYMETHYLTRANSFERASE (Glycine max) | SHMT | ||
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |