(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
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| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
|---|---|---|---|---|---|---|---|
| 4xt7 | TOP | Trimethoprim (DB00440) | Trimethoprim is an antifolate antibiotic often used in combination with sulfamethoxazole to treat a number of infections, including those of the urinary tract, respiratory tract, and gastrointestinal tract. | RV2671 (Mycobacterium tuberculosis (strain atcc 25618 / h37rv)) | RibD_C | ||
| 4xt8 | TMQ | Trimetrexate (DB01157) | Trimetrexate is a folate antagonist used for the treatment of moderate-to-severe Pneumocystis carinii pneumonia (PCP) in immunocompromised patients as an alternative therapy in combination with leucovorin. | RV2671 (Mycobacterium tuberculosis (strain atcc 25618 / h37rv)) | RibD_C | ||
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |