
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)
PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
---|---|---|---|---|---|---|---|
2bfm | TOP | Trimethoprim (DB00440) | Trimethoprim is an antifolate antibiotic often used in combination with sulfamethoxazole to treat a number of infections, including those of the urinary tract, respiratory tract, and gastrointestinal tract. | PTERIDINE REDUCTASE 1 (Leishmania major) | adh_short_C2 | ||
3jq7 | DX2 | Triamterene (DB00384) | Triamterene is a potassium-sparing diuretic used in the treatment of edema and in the management of hypertension. | PTERIDINE REDUCTASE 1 (Trypanosoma brucei) | adh_short_C2 | ||
3jqa | DX4 | Tioguanine (DB00352) | Tioguanine is a purine analogue antineoplastic agent used for the induction of remission, and for remission consolidation in patients with acute nonlymphocytic anemias. | PTERIDINE REDUCTASE 1 (Trypanosoma brucei) | adh_short_C2 | ||
PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |