
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
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PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
---|---|---|---|---|---|---|---|
1q6i | FK5 | Tacrolimus (DB00864) | Tacrolimus is a calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis. | FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA (Escherichia coli) | FKBP_CFKBP_N | ||
3o5r | FK5 | Tacrolimus (DB00864) | Tacrolimus is a calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis. | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP5 (Homo sapiens) | FKBP_C | ||
3rcf | BS4 | Sulfabenzamide (DB09355) | Sulfabenzamide is a sulfonamide antibacterial used as an ingredient in various topical and vaginal preparations to treat certain infections, but has been discontinued by the FDA. | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE F, MITOCHONDRIAL (Homo sapiens) | Pro_isomerase | ||
3tc5 | 3T5 | Betamethasone phosphate (DB14669) | Betamethasone phosphate is a fast acting ester prodrug of a corticosteroid used to treat inflammatory conditions. | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1 (Homo sapiens) | RotamaseWW | ||
3uf8 | FK5 | Tacrolimus (DB00864) | Tacrolimus is a calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis. | UBIQUITIN-LIKE PROTEIN SMT3, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE (Saccharomyces cerevisiae;burkholderia pseudomallei) | FKBP_Cubiquitin | ||
4dri | RAP | Sirolimus (DB00877) | Sirolimus is an immunosuppressant used to prevent organ transplant rejections and to treat lymphangioleiomyomatosis. | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP5;SERINE/THREONINE-PROTEIN KINASE MTOR (Homo sapiens) | FKBP_C | ||
4drj | RAP | Sirolimus (DB00877) | Sirolimus is an immunosuppressant used to prevent organ transplant rejections and to treat lymphangioleiomyomatosis. | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP4;SERINE/THREONINE-PROTEIN KINASE MTOR (Homo sapiens) | FKBP_C | ||
4lax | FK5 | Tacrolimus (DB00864) | Tacrolimus is a calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis. | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP4 (Homo sapiens) | FKBP_C | ||
4nnr | FK5 | Tacrolimus (DB00864) | Tacrolimus is a calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis. | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP2 (Homo sapiens) | FKBP_C | ||
4odo | FK5 | Tacrolimus (DB00864) | Tacrolimus is a calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis. | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SLYD (Thermus thermophilus) | FKBP_C | ||
4odr | FK5 | Tacrolimus (DB00864) | Tacrolimus is a calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis. | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SLYD, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP1A CHIMERA (Thermus thermophilus;homo sapiens) | FKBP_C | ||
5d75 | FK5 | Tacrolimus (DB00864) | Tacrolimus is a calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis. | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP3 (Homo sapiens) | FKBP_C | ||
5gpg | RAP | Sirolimus (DB00877) | Sirolimus is an immunosuppressant used to prevent organ transplant rejections and to treat lymphangioleiomyomatosis. | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP3;SERINE/THREONINE-PROTEIN KINASE MTOR (Homo sapiens) | FKBP_C | ||
5hkg | RAP | Sirolimus (DB00877) | Sirolimus is an immunosuppressant used to prevent organ transplant rejections and to treat lymphangioleiomyomatosis. | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP1B (Homo sapiens) | FKBP_C | ||
5now | L89 | Amifampridine (DB11640) | Amifampridine is a voltage gated potassium channel blocker used to treat Lambert-Eaton myasthenic syndrome. | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (Homo sapiens) | Pro_isomerase | ||
6j2m | FK5 | Tacrolimus (DB00864) | Tacrolimus is a calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis. | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP53 (Arabidopsis thaliana) | FKBP_C | ||
PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |