LIST OF BINDING INTERFACES for query 'MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR' in category 'PROTEIN NAME'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
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PDB Ligand Drug Indication Macromolecule/
Organism
Pfam Binding_Interfaces (View) Details
4r7h P31Pexidartinib
(DB12978)
Pexidartinib is an antitumor agent that is used for the treatment of rare disease tenosynovial giant cell tumors (TGCT) by inhibiting colony-stimulating factor 1 and its receptor.MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR
(Homo sapiens)
PK_Tyr_Ser-Thr
4r7i STIImatinib
(DB00619)
Imatinib is a tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors.MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR
(Homo sapiens)
PK_Tyr_Ser-Thr
PDB Ligand Drug Indication Macromolecule/
Organism
Pfam Binding_Interfaces (View) Details