Ligand ID: P31

Drugbank ID:
Pexidartinib
(DB12978)

Indication:
Pexidartinib is an antitumor agent that is used for the treatment of rare disease tenosynovial giant cell tumors (TGCT) by inhibiting colony-stimulating factor 1 and its receptor.

LIST OF BINDING INTERFACES for query 'P31'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
4R7H_A_P31A1001	4r7h	P31	Pexidartinib (DB12978)	Homo sapiens	MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR	PK_Tyr_Ser-Thr	21	VAL A 548 ARG A 549 TRP A 550 LEU A 588 VAL A 596 ALA A 614 LYS A 616 SER A 632 GLU A 633 ILE A 636 MET A 637 VAL A 647 THR A 663 GLU A 664 TYR A 665 CYS A 666 GLY A 669 LEU A 785 GLY A 795 ASP A 796 PHE A 797	P31 A1001		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["4R7H_A_P31A1001","4r7h","P31","Pexidartinib (DB12978)","Homo sapiens","MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR","PK_Tyr_Ser-Thr",21,"VAL A 548;ARG A 549;TRP A 550;LEU A 588;VAL A 596;ALA A 614;LYS A 616;SER A 632;GLU A 633;ILE A 636;MET A 637;VAL A 647;THR A 663;GLU A 664;TYR A 665;CYS A 666;GLY A 669;LEU A 785;GLY A 795;ASP A 796;PHE A 797","P31 A1001\r"]]